pág. 7659
RESPIRATORY SYMPTOMS ASSOCIATED WITH
CHEMICAL HAZARDS IN OPERATIONAL
PERSONNEL OF THE FOOTWEAR COMPANIES
AT SAN MIGUEL NEIGHBORHOOD OF CÚCUTA,
NORTH OF SANTANDER

SINTOMATOLOGÍA RESPIRATORIA ASOCIADA A LOS

PELIGROS QUÍMICOS EN EL PERSONAL OPERATIVO DEL

SECTOR DE CALZADO EN EL BARRIO SAN MIGUEL CÚCUTA

NORTE DE SANTANDER

Herminio Pabón Trujillo

Corporación Universitaria Minuto de Dios Colombia- Cúcuta

Lina Fernanda Prieto Sanchez

Corporación Universitaria Minuto de Dios Colombia-Cúcuta

Sannia Alejandra Contreras Rodríguez

Corporación Universitaria Minuto de Dios Colombia-Cúcuta

Jhon Alexander Márquez Amado

Corporación Universitaria Minuto de Dios Colombia-Cúcuta

Julieth Calderón Yaruro

Universidad Francisco de Paula Santander- Cúcuta

Sergio Andrés Trigos Bayona

Universidad Francisco de Paula Santander- Cúcuta
pág. 7660
DOI
: https://doi.org/10.37811/cl_rcm.v9i1.16434
Respiratory symptoms associated with chemical hazards in operational

personnel of the footwear
companies at San Miguel neighborhood of Cúcuta,
Nort
h of Santander
Herminio Pabón Trujillo
1
herminio.pabon.t@uniminuto.edu.co

https://orcid.org/0000-0001-5636-4813

Corporación Universitaria Minuto de Dios
Colombia- Cúcuta

Lina Fernanda Prieto Sanchez

lina.prieto
-s@uniminuto.edu.co
https://orcid.org/0009-0003-0046-8922

Corporación Universitaria Minuto de Dios
Colombia-Cúcuta

Sannia Alejandra Contreras Rodríguez

sannia.contreras@uniminuto.edu.co

https://orcid.org/0009-0005-2490-4914

Corporación Universitaria Minuto de Dios
Colombia-Cúcuta

Jhon Alexander Márquez Amado

jhon.marquez-a@uniminuto.edu.co

https://orcid.org/0009-0003-8507-3427

Corporación Universitaria Minuto de Dios
Colombia-Cúcuta

Julieth Calderón Yaruro

juliethxiomaracy@ufps.edu.co

https://orcid.org/0009-0007-1110-8331

Universidad Francisco de Paula Santander- Cúcuta

Sergio Andrés Trigos Bayona

sergio.trigos@uniminuto.edu

https://orcid.org/0009-0002-7067-1689

Universidad Francisco de Paula Santander- Ocaña

ABSTRACT

Health during working life is often affected by different risk factors that cause damage to the body, such

as chemical substances used in different jobs during their execution. In the footwear
companies, it is very
common for them to be used, so health problems for those who are continuously exposed are frequent,

since workers must handle these substances on a daily basis, which leads them to inhale toxic vapors and

be exposed throughout the work day, causing alterations in the airway, increasing the degree of risk due

to the concentration of substances such as solvents and adhesives, exposure, and worker susceptibility,

which can cause from allergic irritation to carcinogenic damage. The objective of the research was to find

out the causes that generate respiratory symptoms produced by chemical substances in operational

workers in the footwear
companies at San Miguel neighborhood in Cúcuta, North of Santander. The study
population consisted of 100 workers and, using the web
-validated sample calculation method, a sample of
80 operational workers from the footwear
companies at San Miguel neighborhood of Cúcuta, North of
Santander
was obtained. A methodology based on a mixed approach was used, which allowed
investigating footwear factories to obtain detailed information on respiratory symptoms associated with

chemical hazards in operational personnel. As a result, workers in the footwear
companies at San Miguel
neighborhood
of Cúcuta, North of Santander are exposed to chemical substances that represent an
unacceptable level of risk. Among the identified hazards are gases and vapors, particulate matter, and the

handling of chemical liquids, each with different levels of probability and acceptability of risk according

to the assessment carried out. In addition, the lack of information, training and awareness of workers to

identify the danger and correct handling of chemical substances, the importance of using PPE (personal

protection elements), increase the risks of suffering health problems.

Keywords:
occupational disease, respiratory symptoms, chemical risk, toxic fumes, risk level
1
Autor principal
Correspondencia:
herminio.pabon.t@uniminuto.edu.co
pág. 7661
Sintomatología Respiratoria Asociada A Los Peligros Químicos En El
Personal Operativo Del Sector De Calzado En El Barrio San Miguel Cúcuta
Norte de Santander

RESUMEN

La salud durante la vida laboral, en la mayoría de las veces es afectada a causa de diferentes factores de
riesgos que generan daños en el organismo, es el caso de las sustancias químicas que son usadas en
diferentes trabajos durante su ejecución. En el sector de calzado es muy común que se utilicen, por lo que
las afecciones en la salud a quienes están expuestos continuamente son frecuentes, puesto que los
trabajadores deben manipular a diario estas sustancias lo que les conlleva a inhalar vapores tóxicos y estar
expuestos durante toda la jornada laboral, provocando alteraciones en la vía área, aumentando el grado de
riesgo debido a la concentración de las sustancias como solventes y adhesivos, la exposición, la
susceptibilidad del trabajador, lo que puede generar desde una irritación alérgica hasta una afectación
cancerígena. El objetivo de la investigación fue conocer las causas generadoras de la sintomatología
respiratoria producida por sustancias químicas en trabajadores operativos del sector de calzado del barrio
San Miguel en Cúcuta, Norte de Santander La población objeto de estudio consistió en 100 trabajadores y
con el método de cálculo de muestra validado en la web, se obtuvo una muestra de 80 personas
trabajadores operativos del sector de calzado del barrio San Miguel en Cúcuta, Norte de Santander Se
utilizó una metodología bajo un enfoque mixto, lo que permitió indagar en las fábricas de calzado para
obtener información detallada sobre la sintomatología respiratoria asociada a los peligros químicos en el
personal operativo. Dejando como resultado que, los trabajadores del sector de calzado del barrio San
Miguel de Cúcuta, Norte Santander, están expuestos a sustancias químicas que representan un nivel de
riesgo inaceptable, entre los peligros identificados se encuentran los gases y vapores, el material
particulado, y la manipulación de líquidos químicos, cada uno con diferentes niveles de probabilidad y
aceptabilidad de riesgo según la evaluación realizada. Además, la poca información, capacitación y
concientización de los trabajadores para identificar la peligrosidad y correcta manipulación de las
sustancias químicas, la importancia del uso de los EPP (elementos de protección personal), aumentan los
riesgos de sufrir afectaciones en la salud.

Palabras Clave: enfermedad laboral, sintomatología respiratoria, riesgo químico, vapores tóxicos, nivel
de riesgo

Artículo recibido 05 enero 2025

Aceptado para publicación:
15 febrero 2025
pág. 7662
INTRODUCTION

People's health during their working life can be affected on multiple occasions by risk factors derived

from exposure to chemical substances in the performance of their daily activities. In the footwear

companies
, workers often face this type of risk, as they constantly handle chemical products, which
expose them to the inhalation of toxic vapours. This exposure can cause problems in the respiratory tract,

ranging from allergic irritations to serious diseases such as cancer. The severity of the impact depen
ds on
factors such as the concentration of the chemicals, the type of substance (such as solvents and adhesives),

the duration of exposure and the individual vulnerability of each worker.

In addition to respiratory problems, prolonged exposure to chemicals generates frequent absences from

work, which directly affects the productivity of companies. In many cases, when absenteeism becomes

recurrent, companies choose to dismiss the worker, leaving them in a vulnerable situation. This is

especially aggravated in the case of those who work in informal conditions, since they do not have health

insurance or occupational risk coverage that allows them to access medical treatment for illnesses relate
d
to their job.

For this reason, the main objective of this document is to analyze the causes of occupational diseases

linked to exposure to chemical substances in workers in the footwear
companies at San Miguel
neighborhood, in Cúcuta,
North of Santander This area is known for its activity in the manufacture of
footwear. The study also seeks to identify the risks, both internal and external, present in footwear

factories, which contribute to the development of respiratory symptoms in workers.

BACKGROUND

The footwear
companies in Bangladesh stands out as an industry with great potential to strengthen the
economy in an export
-focused market. However, to ensure sustainable development in this area, it is
essential to prioritize both the health of workers and the improvement of working conditions.

Footwear manufacturing exposes workers to a variety of risks associated with hazardous compounds,

such as volatile organic compounds, hydrocarbons, toxic solvents, adhesives and polishes. Factors such as

noise, high temperatures, insufficient lighting and ergonomic risks can trigger health problems such as

breathing difficulties, eye irritation, asthma, body pain, hearing loss and other related symptoms.
pág. 7663
This study surveyed more than 400 workers, including operators and supervisors, from twenty selected

factories in the footwear industry in Bangladesh. The results revealed that the most common complaints

among participants were recurrent headaches (41.5%), stomach aches (18.5%), eye problems (11%) and

joint pains (9.5%). Cases of respiratory problems, skin irritations, coughs and hearing conditions were

also identified.

In addition, the findings showed that most workers did not use personal protective equipment or have

access to drinking water at their workplace. Nearly 90% of industries do not offer adequate working

conditions in terms of hygiene, temperature, noise levels and lighting. These unfavourable conditions led

to many employees leaving or changing jobs, mainly due to illness and the unhealthy working

environment.

Direct exposure to hazardous chemicals and ergonomic risks was identified as one of the main causes of

health problems reported in workers in the footwear industry. However, these negative effects could be

reduced with the implementation of more advanced technologies and the replacement of hazardous

chemicals with safer alternatives.

In Bangladesh, approximately 80% of the shoe factories are located in and around Dhaka, while some are

located in Chittagong and Khulna. Within Dhaka, there is a high concentration of small footwear

production units, with 15
-50 workers per factory, in areas such as Siddique Bazaar and Bongshal. This
study identified 20 selected shoe factories in Dhaka and Gazipur, designated by the letters A, B, C,

through T.

Workers in these factories are exposed to various occupational hazards, including organic solvents, whose

inhalation is associated with adverse effects on the lungs, increasing the risk of developing obstructive

and restrictive diseases. Therefore, this study focused on investigating the relationship between exposure

to these solvents, risk factors, and clinical symptoms of impaired lung function in workers in the

companies
.
The research used a cross
-sectional approach and evaluated 134 workers, divided into two groups
according to the area in which they worked: cementation (67 workers) and stock adjustment (67 workers).

Pulmonary function tests were performed to measure values
such as FVC and FEV1/FVC using a
spirometer, in addition to interviews on clinical symptoms, health history and their work history.
pág. 7664
The results indicated that 17% of the participants (23 of 134) suffered from restrictive diseases. The main

risk factors associated with pulmonary symptoms were age, time of occupational exposure and total

accumulation of exposure to chemicals. However, no significant relationship was found between

exposure to organic solvents and serious lung function disorders.

For this analysis, workers with more than five years of experience in the factory and who were exposed to

organic solvents such as acetone and chlorine were included, provided that their chest X
-rays were
normal. Those with a history of tuberculosis or other systemic diseases that may affect lung function were

excluded.

The research process began by randomly selecting workers from the cementing and assembly sections of

the factory. The employees from the cementing section were exposed to acetone, while those from the

materials assembly section worked with acetone and chlorine. Each group consisted of 75 people, for a

total of 150 participants.

All those selected underwent physical tests and spirometry. During these evaluations, 16 workers did not

correctly perform the maneuvers required for spirometry and were excluded from the analysis. Likewise,

in 23 participants restrictive patterns were identified in the test results, so they underwent chest X
-rays,
which did not show any abnormalities.

In total, 134 workers were interviewed using the Indonesian Pneumomobile Project lung function

questionnaire. To measure exposure to organic solvents, specifically acetone and acetone
-chlorine
mixture, air monitoring was carried out in the cementing and assembly areas. Total cumulative exposure

was calculated considering the working time and the recorded exposure level.

The results of the spirometry tests revealed that 23 people (17.1%) had restrictive alterations in lung

function. Of these, 9 worked in the cementing section and 14 in the stock adjustment section.

Air quality monitoring showed acetone levels of 57.90 ppm in the cementing section and 64.80 ppm in

the stock adjustment section, where a chlorine level of 0.001 ppm was also detected. This resulted in a

combined solvent level of 0.13 ppm. All of these values
remained below the permitted Biological Action
Level (BAL).

Regarding the characteristics of the workers, the majority were women (59%) and 89.6% were 23.5 years

old or older, with an average age of 31 years (range 23 to 50 years). In addition, more than half (55%) had
pág. 7665
been working for the company for less than 5 years. Cumulative solvent exposure was 7.7 ppm or more in

52.2% of cases, with an average of 8.46 ppm per year (range 7.05 to 11.28 ppm).

A detailed analysis showed that symptoms of chronic bronchitis were more frequent in the stock

adjustment section (62.7%) than in the cementation section (40.3%). The tables
included in the study
detail the relationships between factors such as age, time of work exposure, habits and symptoms with

lung disorders. However, for the total population, no statistically significant relationships were found (p >

0.05).

Section
-specific results
Stock adjustment: Working time (p = 0.00) and total cumulative exposure (p = 0.00) were factors

significantly associated with pulmonary alterations.

Cementation: Age (p = 0.056), working time (p = 0.00) and total cumulative exposure (p =
0.015) were
shown to be relevant factors.

Multivariate analysis: Variables with a p value < 0.25 were included to perform a multivariate analysis

with logistic regression. This analysis revealed that:

Acetone levels were significant in both sections (p = 0.013).

In the stock adjustment section, cumulative exposure of 7.7 ppm or more and years of work had a

significant impact (p = 0.039).

In the cementing section, the only significant factor was working time of 5.5 years or more (p = 0.008).

Related project

A research project focused on analyzing the exposure to chemicals of 15 workers from the Santina

company, located in the Restrepo neighborhood in Bogotá. This company, dedicated to the manufacture

of leather shoes, exposes its employees to the glue PL
-285, composed mainly of toluene.
The constant use of chemicals in production activities can cause various occupational diseases. According

to the Ministry of Labor (2014), among the most common problems are liver disorders,

glomerulonephritis, and pulmonary hypertension. Objective of the project This degree project aimed to

develop a control in the handling of chemical substances, in order to prevent and evaluate the risks that

exist in the leather footwear workshop due to continuous exposure to these products. The objective is to

prevent
workers from suffering long-term diseases derived from this exposure. To identify the dangers, a
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risk matrix was used. During the visit to the workshop, a checklist was used, photographic records were

taken, and surveys were applied to the 11 exposed employees. The results indicated that workers do not

recognize the chemical risks to which they are exposed, nor the possible consequences of this exposure.

In addition, the company does not provide adequate personal protective equipment (PPE), nor the

necessary conditions in the workplace to mitigate these risks (Joya H., Viveros R., Castro N., 2018).

At the Santina company, located in Bogotá, controls were implemented for the handling of chemical

substances using a quantitative approach. This allowed the problem to be addressed in detail, in order to

prevent possible negative effects on the health of workers due to the handling of these products. A survey

was conducted with 10 workers in the footwear manufacturing area. The survey consisted of 30 questions

related to the work environment, the use of PPE, the handling of chemical substances, the symptoms
that
could occur and the state of order and cleanliness in the workplace. The results showed that:

57% of workers believe that the environmental conditions in their workplace are not adequate. In

addition, 61% do not know how to use personal protective equipment (PPE), since they have not been

provided or trained in its use. Regarding the handling of chemical substances, 66% say that they do so

safely, but only 3% have experienced symptoms related to exposure to these substances.

According to the results obtained, it is crucial to improve environmental conditions, as a poor

environment could significantly increase health risks, especially when handling chemicals. However, a

positive aspect is that 93% of employees believe that the conditions of order and cleanliness in the work

area are good, reflecting that the organization and hygiene in general are adequate.

Another research revealed that constant exposure to organic solvents, especially in the shoe assembly

area, has a negative impact on the health of workers. To address this situation, control measures have

been proposed to minimize the risks related to the handling of these chemicals and thus protect the health

and well
-being of employees.
The objective of this study was to identify the hazards associated with the handling of chemicals, assess

the qualitative exposure to these products and propose specific controls for the leather footwear company.

It was a descriptive and cross
-sectional study, whose methodology included direct observation of the
production process in the assembly area. In addition, a survey with closed questions was applied to a
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sample of 61 workers, who are part of a group of 151 people exposed to chemical solvents for more than

8 hours a day.

The results of the qualitative assessment indicated that the highest risk chemicals are Solvent C
-101 and
Regia PC 2000. Due to the high levels of danger they represent, it is urgent to intervene in the tasks that

involve the handling of these substances. To facilitate the identification of these critical tasks, a flowchart

was developed to allow a more effective intervention in the chemical risks present in the work area.

According to Castilla, A.; Paredes, A. (2021) in a company, the concern to maintain c
ontrol and
management of the possible risks that can affect the health of its workers, raw materials and the financial

part stands out. It is therefore logical that accidents and occupational diseases are causes that stop the

development of company activities, which impacts production, the fulfillment of objectives and status in

the market, adding to this the work, family and social impact of the worker who suffers the affectation in

his health.

Job desertions among professionals are often related to accidents and illnesses such as chronic stress,

muscle pain, and fatigue. These conditions cause employees to miss work, which directly impacts the

company's performance and efficiency (Boada & Ficapal
-Cusí, 2012). In addition, the World Health
Organization points out that many companies, due to economic concerns, are reluctant to invest in an

Occupational Health and Safety Management System (OHSMS), although this investment could prevent

accidents and
illnesses among workers.
The value of human resources and labor is fundamental for any organization, so it is vital to monitor the

well
-being of employees and the organizational environment. This not only protects the physical and
psychological health of workers, but also the efficiency and sustainability of the company (Chan & Canul,

2018). Hence the importance of implementing an OSHMS that includes medicine, safety, and industrial

hygiene actions. The objective is to understand, control and improve the health conditions of employ
ees,
ensuring a safe and healthy work environment (Molano & Arévalo, 2013).

In the case of Calzado ANYELME, according to the study carried out by Castilla and Paredes (2021),

various chemicals and sharp tools are used during the footwear manufacturing process, high temperatures

are handled and workers work long hours in positions that are not always ergonomic. All this makes the

prevention of occupational risks a priority for the company. Therefore, it is necessary to carry out a series
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of procedures, such as the planning of preventive and corrective measures, the identification of hazardous

actions, risk assessment and the improvement of work areas. In addition, the health status of the worker

must be known when entering the company, in order to reduce the risks that may affect their safety, thus

complying with Decree 1443 of 2014.

It is essential that the investigations and design of the SG
-SST focus on knowing the current conditions of
the administrative and productive areas of each company. This involves identifying, evaluating and

assessing the risks, which will lead to the planning of an adequate system with objectives, clear policies

and the development of risk matrices for each work section. In addition, a coexistence and well
-being
committee must be formed to ensure compliance with the standards and regulate all aspects of the
SG-
SST.

The study entitled ''Planning of a Safety and Health Management System at Work according to Decree

1072 of 2015 in the company Calzado ANYELME SAS, located in Cúcuta, Nort
h of Santander'' used a
mixed methodological approach, combining two different approaches: qualitative and quantitative.

In the context of research, it is essential to understand the basis of the studies. According to Hernández

and Mendoza (2018), research studies are divided into several types: exploratory, which focus on little
-
studied or not yet addressed phenomena; descriptive, which seek to specify, measure, evaluate and

quantify variables and phenomena within a given context; correlational, which aim to analyze the

relationship between two or more variables or phenomena; and explanatory, whose purpose is to

understand t
he causes and factors that explain the occurrence of certain phenomena in a specific context.
In the case of Calzado ANYELME SAS, an ''Initial Evaluation of the Minimum Standards established in

Resolution 0312 of 2019, article 16'' was carried out, which was fully applied, allowing for a detailed

overview of the current state of the company.

With the collaboration of the Occupational Risk Administrator SURA, compliance in matters of safety

and health at work was verified. This initial assessment followed the PDCA cycle (Plan, Do, Check, Act),

and the company must develop actions in accordance with current regulations, complying with each

established section.

The assessment is presented in a table with scores that reflect compliance with each phase of the cycle:

Plan (25 points), Do (60 points), Check (5 points) and Act (10 points), with a total of 100 possible points.