Chemical-Quantum Analysis Of The Anticancer Potential Of Rhodionin Present In The Plant Rhodiola Rosea Vs. Amino Acids Of The Human Body

Rhodiola rosea ( R. rosea ) extract has molecular contrast mechanisms, which have normal physiological functions. Extracts of R. rosea have anticancer potentials. Rhodiodin (RDN) is a flavonoid compound found in Rhodiola plants. The aim was to analyze the anticancer potential of rodionin present in the R. rosea plant by quantum chemistry. Hyperchem software was used as a quantum chemistry simulator. The fundamental basis of quantum calculations was the electron transfer coefficient (ETC) theory. We can see the ETCs ordered according to the quantum well. The substance lies at the bottom of the quantum well. This situation indicates that the probability of oxidative interactions occurring is very high. We found that the RDN is a potent oxidant of AAs in the human body; for this reason, it has potential as an anticancer chemotherapeutic agent.


INTRODUCTION
Natural compounds extracted from herbs are used to prevent or treat different diseases.Cancer is included in these diseases.In addition, these natural compounds are an alternative to drug consumption.The researchers conducted studies on plant compounds.They aimed to find substances with selective cytotoxicity in abnormal cells.Phenolic compounds are important secondary metabolites of plants.(Teodor et al., 2020); (Kwon, 2018); (Alamgir, 2018) The plant of the genus R. (Crassulaceae) comprises approximately 96 species.R. rosea is a popular plant in traditional medical systems in the Nordic countries, Eastern Europe, and Asia.This plant has medicinal properties such as stimulating the nervous system, reducing depression, improving work performance, eliminating fatigue, and preventing altitude sickness.(T.Li & Zhang, 2008); (Petsalo et al 2006); (Khanum et al 2005a); (Panossian et al 2010b) The researchers conducted a study on the content and location of the phenolic compounds of R.
rosea.The study focused on phenylpropanoid compounds.The plant material used in the introduction experiment was obtained by the in vitro method.The researchers used the HPLC method to identify the phenolic compounds.The compounds identified were: gallic acid, rosavin, rosin, cinnamon alcohol, rhodopsin, RDN, and kaempferol.RDN is a flavonoid compound found in R. rosea plants.(Erst et al. 2021); (Kurkin, 2013b); (ALtAntsetseG, K et al 2007) Researchers have studied the molecular mechanisms of action of R. rosea extracts.R. rosea extracts have molecular contrast mechanisms, and these have normal physiological functions.Extracts of R. rosea have anticancer potentials.These inhibit the mTOR pathway and further reduce angiogenesis by downregulating HIF-1α/HIF-2α expression.(Y.Li et al. 2017b); (Liu et al. 2011) Cancer is one of the leading causes of death in the world.Cancer has a prevalence of >10 million deaths annually.Current cancer treatments include surgery, radiation, and chemotherapy drugs, often killing healthy cells and producing toxicity in patients.(Zaimy et al. 2017) (Hausman, 2019); (Torre et al 2016); (Gilbertson, 2011) pág.9093

MATERIAL AND METHODS
Hyperchem software was used as a quantum chemistry simulator.The fundamental basis of quantum calculations was the theory of the ETC.In tables 1-2.The parameters used in this simulation are specified.
The Plot Molecular Graph method in three dimensions was used to calculate the electrostatic potential (EP).
Finally, the ETC was calculated by dividing the band gap by the EP.
As there are too many calculations, only the tables, whisker, and box diagrams are presented in this article.If you would like more information, please contact Dr. Manuel González Pérez.Where To show a summary of 61 interactions between the RDN and the 20 AAs of the human body, we used whisker and box diagrams.
In Table 1, we can see the ETCs ordered according to the quantum well.It is observed that the RDN is at the bottom of the well.This location leads us to infer that RDN is a long-acting substance so this substance cannot be eliminated by the biological organism without   Thesis.The diagrams (Figure 5) show that the probability of oxidative interactions occurring is very high.This leads us to infer that RDN is a potent oxidant of AAs in the human body, for this reason it has a potential as an anticancer chemotherapeutic agent.
Corollary.We found outside our target that the RDN is at the bottom of the well.This location leads us to infer that RDN is a long-acting substance so this substance cannot be eliminated by the biological organism without complications.

ACKNOWLEDGMENTS
To our parents, who with their example of tenacity, honesty and love guide us along the path of life.
pág. 9101 To the Delfín program for giving us the opportunity to scientifically investigate these substances that are so important for stopping cancer.
To the Technological University of Tecamachalco for providing us with its facilities, intellectual and logistical support in general, to develop this important research.
To our teachers, unconditional guides to the progress of us, our community, and our country Mexico.

Figure 1
Figure1presents the quantum well of the interactions through its ETC.On the left side, the

Figure 1 .Figure 2 9096 Figure 2 .
Figure 1.Quantum well.Interpretation of the interactions in the four statistical

Figure 3 9097 Figure 3 .
Figure3shows the results of the simulated characterization of C13 Nuclear Magnetic Resonance.

Figure 4
Figure 4 shows us the RDN molecule characterized by its different quantum concepts.This

Figure 5 .
Figure 5. Whisker diagrams of the CTEs of chemical-quantum interactions.The lower