Abordaje Fisioterapéutico en Pacientes con Neuropatía Periférica Secundaria a Quimioterapia con Vincristina: Una Revisión Sistemática
Palabras clave:
ejercicio, dolor, neuropatía periférica inducida por quimioterapia
Resumen
Se ha descrito que la vincristina se caracteriza por provocar una neuropatía axonal sensitiva, debido a los efectos neurotóxicos de los alcaloides de la vinca que afectan a nivel periférico. El objetivo de este trabajo es identificar qué abordaje fisioterapéutico es más efectivo para disminuir los síntomas de la neuropatía periférica inducida por la vincristina. Este trabajo es un artículo de revisión sistemática, en la cual se incluyeron tres revisiones sistemáticas, un ensayo controlado aleatorizado, un ensayo exploratorio aleatorizado y un estudio aleatorizado. Los estudios tienen grupos de intervención en el cual comparan la terapia vibratoria de todo el cuerpo, compresas frías y el ejercicio terapéutico y los grupos comparadores evaluados recibieron atención estándar y folletos de información de actividad física en casa. El tratamiento más efectivo de acuerdo con la información descrita es el ejercicio terapéutico, mostrando reducción significativa en los síntomas de la neuropatía periférica.
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Begoña Pérez Valderrama Jesús Corral Jaime Ana Ma Casas Fernández de Tejerina. NEUROTOXICIDAD POR QUIMIOTERAPIA (2015).
https://www.aeped.es/comite-medicamentos/pediamecum/vincristina
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Cancer Resources from OncoLink, Treatment, Research, Coping, Clinical Trials, Prevention. (s. f.). Vincristine (Oncovin®, Vincasar PFS®, VCR) | OncoLink. University Of Pennsylvania - OncoLink. https://es.oncolink.org/tratamiento-del-cancer/oncolink-rx/vincristine-oncovin-r-vincasar-pfs-r-vcr
Día Mundial contra el Cáncer 2024: Por unos cuidados más justos. (s. f.). OPS/OMS | Organización Panamericana de la Salud. https://www.paho.org/es/campanas/dia-mundial-contra-cancer-2024-por-unos-cuidados-mas-justos
Dixit, S., Tapia, V., Sepúlveda, C., Olate, D., Berríos-Contreras, L., Lorca, L. A., Alqahtani, A. S., & Ribeiro, I. L. (2023). Effectiveness of a Therapeutic Exercise Program to Improve the Symptoms of Peripheral Neuropathy during Chemotherapy: Systematic Review of Randomized Clinical Trials. Life (Basel, Switzerland), 13(2), 262. https://doi.org/10.3390/life13020262
Gewandter, J. S., Chaudari, J., Ibegbu, C., Kitt, R., Serventi, J., Burke, J., Culakova, E., Kolb, N., Sluka, K. A., Tejani, M. A., & Mohile, N. A. (2019). Wireless transcutaneous electrical nerve stimulation device for chemotherapy-induced peripheral neuropathy: an open-label feasibility study. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer, 27(5), 1765–1774. https://doi.org/10.1007/s00520-018-4424-6
Gibson, W., Wand, B. M., & O'Connell, N. E. (2017). Transcutaneous electrical nerve stimulation (TENS) for neuropathic pain in adults. The Cochrane database of systematic reviews, 9(9), CD011976. https://doi.org/10.1002/14651858.CD011976.pub2
INEGI. (2 de febrero de 2024). ESTADÍSTICAS A PROPÓSITO DEL DÍA MUNDIAL CONTRA EL CÁNCER (4 de febrero) Datos nacionales.
https://www.inegi.org.mx/contenidos/saladeprensa/aproposito/2024/EAP_CANCER24.pdf,
Jones, L. W., Fels, D. R., West, M., Allen, J. D., Broadwater, G., Barry, W. T., Wilke, L. G., Masko, E., Douglas, P. S., Dash, R. C., Povsic, T. J., Peppercorn, J., Marcom, P. K., Blackwell, K. L., Kimmick, G., Turkington, T. G., & Dewhirst, M. W. (2013). Modulation of circulating angiogenic factors and tumor biology by aerobic training in breast cancer patients receiving neoadjuvant chemotherapy. Cancer prevention research (Philadelphia, Pa.), 6(9), 925–937. https://doi.org/10.1158/1940-6207.CAPR-12-0416
Kleckner, I. R., Kamen, C., Gewandter, J. S., Mohile, N. A., Heckler, C. E., Culakova, E., Fung, C., Janelsins, M. C., Asare, M., Lin, P. J., Reddy, P. S., Giguere, J., Berenberg, J., Kesler, S. R., & Mustian, K. M. (2018). Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer, 26(4), 1019–1028. https://doi.org/10.1007/s00520-017-4013-0
Alegría Bernal, C. M. (2024). La Norma Iso 21001 Y Su Aplicación En El Ámbito De La Educación Superior. Estudios Y Perspectivas Revista Científica Y Académica , 4(2), 374–389. https://doi.org/10.61384/r.c.a.v4i2.228
Zeballos , F. (2024). Shock Séptico en Terapia Intensiva Adulto del Hospital San Juan de Dios de la Ciudad de Tarija: Revista Científica de Salud y Desarrollo Humano. Revista Científica De Salud Y Desarrollo Humano, 5(2), 179–191. https://doi.org/10.61368/r.s.d.h.v5i2.128
Gallegos Medina, S. L. (2024). Desarrollo Sociocultural durante la Primera Infancia desde una Perspectiva Psicológica. Emergentes - Revista Científica, 4(1), 12–21. https://doi.org/10.60112/erc.v4i1.86
Montes López, V. (2023). Socioeconomic Inequalities in Health: A Challenge for Equity. Revista Veritas De Difusão Científica, 4(1), 18–29. https://doi.org/10.61616/rvdc.v4i1.35
Da Silva Santos , F., & López Vargas , R. (2020). Efecto del Estrés en la Función Inmune en Pacientes con Enfermedades Autoinmunes: una Revisión de Estudios Latinoamericanos. Revista Científica De Salud Y Desarrollo Humano, 1(1), 46–59. https://doi.org/10.61368/r.s.d.h.v1i1.9
Kneis, S., Wehrle, A., Müller, J., Maurer, C., Ihorst, G., Gollhofer, A., & Bertz, H. (2019). It's never too late - balance and endurance training improves functional performance, quality of life, and alleviates neuropathic symptoms in cancer survivors suffering from chemotherapy-induced peripheral neuropathy: results of a randomized controlled trial. BMC cancer, 19(1), 414. https://doi.org/10.1186/s12885-019-5522-7
Laforgia, M., Laface, C., Calabrò, C., Ferraiuolo, S., Ungaro, V., Tricarico, D., Gadaleta, C. D., Nardulli, P., & Ranieri, G. (2021). Peripheral Neuropathy under Oncologic Therapies: A Literature Review on Pathogenetic Mechanisms. International journal of molecular sciences, 22(4), 1980. https://doi.org/10.3390/ijms22041980
Mezzanotte, J. N., Grimm, M., Shinde, N. V., Nolan, T., Worthen-Chaudhari, L., Williams, N. O., & Lustberg, M. B. (2022). Updates in the Treatment of Chemotherapy-Induced Peripheral Neuropathy. Current treatment options in oncology, 23(1), 29–42. https://doi.org/10.1007/s11864-021-00926-0
Staff, N. P., Grisold, A., Grisold, W., & Windebank, A. J. (2017). Chemotherapy-induced peripheral neuropathy: A current review. Annals of neurology, 81(6), 772–781. https://doi.org/10.1002/ana.24951
Şimşek, N. Y., & Demir, A. (2021). Cold Application and Exercise on Development of Peripheral Neuropathy during Taxane Chemotherapy in Breast Cancer Patients: A Randomized Controlled Trial. Asia-Pacific journal of oncology nursing, 8(3), 255–266. https://doi.org/10.4103/apjon.apjon-2075
Schönsteiner, S. S., Bauder Mißbach, H., Benner, A., Mack, S., Hamel, T., Orth, M., Landwehrmeyer, B., Süßmuth, S. D., Geitner, C., Mayer-Steinacker, R., Riester, A., Prokein, A., Erhardt, E., Kunecki, J., Eisenschink, A. M., Rawer, R., Döhner, H., Kirchner, E., & Schlenk, R. F. (2017). A randomized exploratory phase 2 study in patients with chemotherapy-related peripheral neuropathy evaluating whole-body vibration training as adjunct to an integrated program including massage, passive mobilization and physical exercises. Experimental hematology & oncology, 6, 5. https://doi.org/10.1186/s40164-017-0065-6
Püsküllüoğlu, M., Tomaszewski, K. A., Grela-Wojewoda, A., Pacholczak-Madej, R., & Ebner, F. (2022). Effects of Transcutaneous Electrical Nerve Stimulation on Pain and Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: A Systematic Review. Medicina (Kaunas, Lithuania), 58(2), 284. https://doi.org/10.3390/medicina58020284
Tamburin, S., Park, S. B., Schenone, A., Mantovani, E., Hamedani, M., Alberti, P., Yildiz-Kabak, V., Kleckner, I. R., Kolb, N., Mazzucchelli, M., McNeish, B. L., Argyriou, A. A., Cavaletti, G., Hoke, A., & Toxic Neuropathy Consortium (2022). Rehabilitation, exercise, and related non-pharmacological interventions for chemotherapy-induced peripheral neurotoxicity: Systematic review and evidence-based recommendations. Critical reviews in oncology/hematology, 171, 103575. https://doi.org/10.1016/j.critrevonc.2021.103575
Vincristina | Asociación Española de Pediatría. (7 de abril de 2021) (s. f.). https://www.aeped.es/comite-
World Health Organization: WHO. (2022, 3 febrero). Cáncer.
https://www.who.int/es/news-room/fact-sheets/detail/cancer
Zhang S. (2021). Chemotherapy-induced peripheral neuropathy and rehabilitation: A review. Seminars in oncology, 48(3), 193–207. https://doi.org/10.1053/j.seminoncol.2021.09.004
https://www.aeped.es/comite-medicamentos/pediamecum/vincristina
Beijers, A. J. M., Bonhof, C. S., Mols, F., Ophorst, J., de Vos-Geelen, J., Jacobs, E. M. G., van de Poll-Franse, L. V., & Vreugdenhil, G. (2020). Multicenter randomized controlled trial to evaluate the efficacy and tolerability of frozen gloves for the prevention of chemotherapy-induced peripheral neuropathy. Annals of oncology: official journal of the European Society for Medical Oncology, 31(1), 131–136. https://doi.org/10.1016/j.annonc.2019.09.006
Cancer Resources from OncoLink, Treatment, Research, Coping, Clinical Trials, Prevention. (s. f.). Vincristine (Oncovin®, Vincasar PFS®, VCR) | OncoLink. University Of Pennsylvania - OncoLink. https://es.oncolink.org/tratamiento-del-cancer/oncolink-rx/vincristine-oncovin-r-vincasar-pfs-r-vcr
Día Mundial contra el Cáncer 2024: Por unos cuidados más justos. (s. f.). OPS/OMS | Organización Panamericana de la Salud. https://www.paho.org/es/campanas/dia-mundial-contra-cancer-2024-por-unos-cuidados-mas-justos
Dixit, S., Tapia, V., Sepúlveda, C., Olate, D., Berríos-Contreras, L., Lorca, L. A., Alqahtani, A. S., & Ribeiro, I. L. (2023). Effectiveness of a Therapeutic Exercise Program to Improve the Symptoms of Peripheral Neuropathy during Chemotherapy: Systematic Review of Randomized Clinical Trials. Life (Basel, Switzerland), 13(2), 262. https://doi.org/10.3390/life13020262
Gewandter, J. S., Chaudari, J., Ibegbu, C., Kitt, R., Serventi, J., Burke, J., Culakova, E., Kolb, N., Sluka, K. A., Tejani, M. A., & Mohile, N. A. (2019). Wireless transcutaneous electrical nerve stimulation device for chemotherapy-induced peripheral neuropathy: an open-label feasibility study. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer, 27(5), 1765–1774. https://doi.org/10.1007/s00520-018-4424-6
Gibson, W., Wand, B. M., & O'Connell, N. E. (2017). Transcutaneous electrical nerve stimulation (TENS) for neuropathic pain in adults. The Cochrane database of systematic reviews, 9(9), CD011976. https://doi.org/10.1002/14651858.CD011976.pub2
INEGI. (2 de febrero de 2024). ESTADÍSTICAS A PROPÓSITO DEL DÍA MUNDIAL CONTRA EL CÁNCER (4 de febrero) Datos nacionales.
https://www.inegi.org.mx/contenidos/saladeprensa/aproposito/2024/EAP_CANCER24.pdf,
Jones, L. W., Fels, D. R., West, M., Allen, J. D., Broadwater, G., Barry, W. T., Wilke, L. G., Masko, E., Douglas, P. S., Dash, R. C., Povsic, T. J., Peppercorn, J., Marcom, P. K., Blackwell, K. L., Kimmick, G., Turkington, T. G., & Dewhirst, M. W. (2013). Modulation of circulating angiogenic factors and tumor biology by aerobic training in breast cancer patients receiving neoadjuvant chemotherapy. Cancer prevention research (Philadelphia, Pa.), 6(9), 925–937. https://doi.org/10.1158/1940-6207.CAPR-12-0416
Kleckner, I. R., Kamen, C., Gewandter, J. S., Mohile, N. A., Heckler, C. E., Culakova, E., Fung, C., Janelsins, M. C., Asare, M., Lin, P. J., Reddy, P. S., Giguere, J., Berenberg, J., Kesler, S. R., & Mustian, K. M. (2018). Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: a multicenter, randomized controlled trial. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer, 26(4), 1019–1028. https://doi.org/10.1007/s00520-017-4013-0
Alegría Bernal, C. M. (2024). La Norma Iso 21001 Y Su Aplicación En El Ámbito De La Educación Superior. Estudios Y Perspectivas Revista Científica Y Académica , 4(2), 374–389. https://doi.org/10.61384/r.c.a.v4i2.228
Zeballos , F. (2024). Shock Séptico en Terapia Intensiva Adulto del Hospital San Juan de Dios de la Ciudad de Tarija: Revista Científica de Salud y Desarrollo Humano. Revista Científica De Salud Y Desarrollo Humano, 5(2), 179–191. https://doi.org/10.61368/r.s.d.h.v5i2.128
Gallegos Medina, S. L. (2024). Desarrollo Sociocultural durante la Primera Infancia desde una Perspectiva Psicológica. Emergentes - Revista Científica, 4(1), 12–21. https://doi.org/10.60112/erc.v4i1.86
Montes López, V. (2023). Socioeconomic Inequalities in Health: A Challenge for Equity. Revista Veritas De Difusão Científica, 4(1), 18–29. https://doi.org/10.61616/rvdc.v4i1.35
Da Silva Santos , F., & López Vargas , R. (2020). Efecto del Estrés en la Función Inmune en Pacientes con Enfermedades Autoinmunes: una Revisión de Estudios Latinoamericanos. Revista Científica De Salud Y Desarrollo Humano, 1(1), 46–59. https://doi.org/10.61368/r.s.d.h.v1i1.9
Kneis, S., Wehrle, A., Müller, J., Maurer, C., Ihorst, G., Gollhofer, A., & Bertz, H. (2019). It's never too late - balance and endurance training improves functional performance, quality of life, and alleviates neuropathic symptoms in cancer survivors suffering from chemotherapy-induced peripheral neuropathy: results of a randomized controlled trial. BMC cancer, 19(1), 414. https://doi.org/10.1186/s12885-019-5522-7
Laforgia, M., Laface, C., Calabrò, C., Ferraiuolo, S., Ungaro, V., Tricarico, D., Gadaleta, C. D., Nardulli, P., & Ranieri, G. (2021). Peripheral Neuropathy under Oncologic Therapies: A Literature Review on Pathogenetic Mechanisms. International journal of molecular sciences, 22(4), 1980. https://doi.org/10.3390/ijms22041980
Mezzanotte, J. N., Grimm, M., Shinde, N. V., Nolan, T., Worthen-Chaudhari, L., Williams, N. O., & Lustberg, M. B. (2022). Updates in the Treatment of Chemotherapy-Induced Peripheral Neuropathy. Current treatment options in oncology, 23(1), 29–42. https://doi.org/10.1007/s11864-021-00926-0
Staff, N. P., Grisold, A., Grisold, W., & Windebank, A. J. (2017). Chemotherapy-induced peripheral neuropathy: A current review. Annals of neurology, 81(6), 772–781. https://doi.org/10.1002/ana.24951
Şimşek, N. Y., & Demir, A. (2021). Cold Application and Exercise on Development of Peripheral Neuropathy during Taxane Chemotherapy in Breast Cancer Patients: A Randomized Controlled Trial. Asia-Pacific journal of oncology nursing, 8(3), 255–266. https://doi.org/10.4103/apjon.apjon-2075
Schönsteiner, S. S., Bauder Mißbach, H., Benner, A., Mack, S., Hamel, T., Orth, M., Landwehrmeyer, B., Süßmuth, S. D., Geitner, C., Mayer-Steinacker, R., Riester, A., Prokein, A., Erhardt, E., Kunecki, J., Eisenschink, A. M., Rawer, R., Döhner, H., Kirchner, E., & Schlenk, R. F. (2017). A randomized exploratory phase 2 study in patients with chemotherapy-related peripheral neuropathy evaluating whole-body vibration training as adjunct to an integrated program including massage, passive mobilization and physical exercises. Experimental hematology & oncology, 6, 5. https://doi.org/10.1186/s40164-017-0065-6
Püsküllüoğlu, M., Tomaszewski, K. A., Grela-Wojewoda, A., Pacholczak-Madej, R., & Ebner, F. (2022). Effects of Transcutaneous Electrical Nerve Stimulation on Pain and Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: A Systematic Review. Medicina (Kaunas, Lithuania), 58(2), 284. https://doi.org/10.3390/medicina58020284
Tamburin, S., Park, S. B., Schenone, A., Mantovani, E., Hamedani, M., Alberti, P., Yildiz-Kabak, V., Kleckner, I. R., Kolb, N., Mazzucchelli, M., McNeish, B. L., Argyriou, A. A., Cavaletti, G., Hoke, A., & Toxic Neuropathy Consortium (2022). Rehabilitation, exercise, and related non-pharmacological interventions for chemotherapy-induced peripheral neurotoxicity: Systematic review and evidence-based recommendations. Critical reviews in oncology/hematology, 171, 103575. https://doi.org/10.1016/j.critrevonc.2021.103575
Vincristina | Asociación Española de Pediatría. (7 de abril de 2021) (s. f.). https://www.aeped.es/comite-
World Health Organization: WHO. (2022, 3 febrero). Cáncer.
https://www.who.int/es/news-room/fact-sheets/detail/cancer
Zhang S. (2021). Chemotherapy-induced peripheral neuropathy and rehabilitation: A review. Seminars in oncology, 48(3), 193–207. https://doi.org/10.1053/j.seminoncol.2021.09.004
Publicado
2024-06-27
Cómo citar
Alarcón Juárez, M., & Aguilar Blanco, J. A. (2024). Abordaje Fisioterapéutico en Pacientes con Neuropatía Periférica Secundaria a Quimioterapia con Vincristina: Una Revisión Sistemática. Ciencia Latina Revista Científica Multidisciplinar, 8(3), 4955-4971. https://doi.org/10.37811/cl_rcm.v8i3.11698
Número
Sección
Ciencias de la Salud
Derechos de autor 2024 Melina Alarcón Juárez, Jeimys Andrea Aguilar Blanco
Esta obra está bajo licencia internacional Creative Commons Reconocimiento 4.0.
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