Perfiles de Expresión en Cáncer: Del RNA a Tratamientos Personalizados
Resumen
El RNA desempeña un papel crucial en la expresión de los genes. Dentro del grupo de los RNA, se encuentran los miRNA, pequeñas moléculas de RNA que tienen la capacidad de regular la actividad de los genes. A diferencia del RNA mensajero (RNAm), que codifica proteínas, los miRNA no se traducen en proteínas, sino que se unen a RNAm específicos para regular su expresión. Estos pequeños fragmentos de RNA pueden inhibir la traducción del RNAm o inducir su degradación, lo que lleva a una disminución en la producción de la proteína codificada por ese RNAm. En este capítulo, exploraremos en detalle la fascinante función de los miRNA en la regulación génica, la interacción entre las mismas moléculas y su implicación en el cáncer. Investigaremos cómo los miRNA pueden influir en el desarrollo, diagnóstico y tratamiento del cáncer de mama y cómo su estudio podría abrir nuevas perspectivas terapéuticas en el campo de la medicina.
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Derechos de autor 2026 Jimena Garibay , Yarah P. Ángeles Cortes , Jonnathan G. Santillán Benitez
Esta obra está bajo licencia internacional Creative Commons Reconocimiento 4.0.
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