Factores clínicos asociados a reinfección de covid-19 en personal de salud que labora en el área covid del estado de Hidalgo
Resumen
A finales del año 2019 comienzan los primeros casos de COVID-19 cuyo agente causal es el virus SARS-CoV 2. Desde entonces y hasta la fecha el mundo sigue padeciéndolo y aún hay muchas interrogantes sin contestar, por ejemplo ¿cuáles son los factores clínicos favorecen la infección y la reinfección? Para ello es necesario trabajar con personas expuestas, como es el personal de salud. Objetivo: Identificar los factores clínicos qué se asociaban a COVID-19 en personal de Salud. Metodología: Para ello se aplicó una encuesta al personal de salud que se encontraba atendiendo a pacientes con COVID-19. Fue un total de 150 personas estudiadas como personal de salud, entre ellos 117 mujeres y 33 hombres. Los resultados demostraron que los hombres fueron más susceptibles a la infección que las mujeres, las comorbilidades favorecen la sintomatología a COVID-19, mayormente en los hombres; la vacunación no protege contra la infección por el virus; los infectados se reinfectan en más de una ocasión y hasta por seis meses. Este trabajo permite concluir hay que tener más cuidado en los hombres que en las mujeres en casos de COVID ya que es posible que no se elimine el virus en varios meses.
Descargas
Citas
Akiyama, S., Hamdeh, S., Micic, D., & Sakuraba, A. (2021). Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis. Annals of the Rheumatic Diseases, 80(3), 384–391.
Cao, C., Cai, Z., Xiao, X., Rao, J., Chen, J., Hu, N., … Xue, Y. (2021). The architecture of the SARS-CoV-2 RNA genome inside virion. Nature Communications 2021 12:1, 12(1), 1–14.
Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., … Zhang, L. (2020). Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet, 395(10223), 507–513.
Costa, A. O. C., Neto, H. de C. A., Nunes, A. P. L., de Castro, R. D., & de Almeida, R. N. (2021). Covid-19: Is reinfection possible? EXCLI Journal, Vol. 20, pp. 522–536.
Dao, T. L., Hoang, V. T., & Gautret, P. (2021). Recurrence of SARS-CoV-2 viral RNA in recovered COVID-19 patients: a narrative review. European Journal of Clinical Microbiology and Infectious Diseases, 40(1), 13–25.
Duggan, N. M., Ludy, S. M., Shannon, B. C., Reisner, A. T., & Wilcox, S. R. (2020). A case report of possible novel coronavirus 2019 reinfection. Icpcovid.Com, 39, 256.e1-256.e3.
Ejaz, H., Alsrhani, A., Zafar, A., Javed, H., Junaid, K., Abdalla, A. E., … Younas, S. (2020). COVID-19 and comorbidities: Deleterious impact on infected patients. Journal of Infection and Public Health, 13(12), 1833–1839.
Elrashdy, F., Aljaddawi, A. A., Redwan, E. M., & Uversky, V. N. (2020). On the potential role of exosomes in the COVID-19 reinfection/reactivation opportunity.
Fernández, J. A. M., & Chew, R. M. W. (2021). Generalidades, aspectos clínicos y de prevención sobre COVID-19: México y Latinoamérica. Universitas Medica, 62(3).
Gaiha, S. M., Cheng, J., & Halpern-Felsher, B. (2020). Association Between Youth Smoking, Electronic Cigarette Use, and COVID-19. Journal of Adolescent Health, 67(4), 519–523.
Gousseff, M., Penot, P., Gallay, L., Batisse, D., Benech, N., Bouiller, K., … behalf of the COCOREC study group, in. (2020). Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound? Journal of Infection, 81, 816–846.
Guan, W., Ni, Z., Hu, Y., Liang, W., Ou, C., He, J., … Zhong, N. (2020a). Clinical Characteristics of Coronavirus Disease 2019 in China. New England Journal of Medicine, 382(18), 1708–1720.
Guan, W., Ni, Z., Hu, Y., Liang, W., Ou, C., He, J., … Zhong, N. (2020b). Clinical Characteristics of Coronavirus Disease 2019 in China. New England Journal of Medicine, 382(18), 1708–1720.
Ioannou, G. N., Locke, E., Green, P., Berry, K., O’Hare, A. M., Shah, J. A., … Fan, V. S. (2020). Risk Factors for Hospitalization, Mechanical Ventilation, or Death Among 10 131 US Veterans With SARS-CoV-2 Infection. JAMA Network Open, 3(9), e2022310.
Jordan, R. E., Adab, P., & Cheng, K. K. (2020, March 26). Covid-19: Risk factors for severe disease and death. The BMJ, Vol. 368.
Kang, H., Wang, Y., Tong, Z., & Liu, X. (2020). Retest positive for SARS‐CoV‐2 RNA of “recovered” patients with COVID‐19: Persistence, sampling issues, or re‐infection? Journal of Medical Virology, 92(11), 2263–2265.
Kiyuka, P. K., Agoti, C. N., Munywoki, P. K., Njeru, R., Bett, A., Otieno, J. R., … Cotten, M. (2018). Human Coronavirus NL63 Molecular Epidemiology and Evolutionary Patterns in Rural Coastal Kenya. The Journal of Infectious Diseases, 217(11), 1728–1739.
Lan, L., Xu, D., Ye, G., Xia, C., Wang, S., Li, Y., & Xu, H. (2020). Positive RT-PCR Test Results in Patients Recovered from COVID-19. JAMA - Journal of the American Medical Association, 323(15), 1502–1503.
Laue, M., Kauter, A., Hoffmann, T., Möller, L., Michel, J., & Nitsche, A. (2021). Morphometry of SARS-CoV and SARS-CoV-2 particles in ultrathin plastic sections of infected Vero cell cultures. Scientific Reports, 11(1), 3515.
Lu, R., Zhao, X., Li, J., Niu, P., Yang, B., Wu, H., … Tan, W. (2020). Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. The Lancet, 395(10224), 565–574.
Luo, A. (2020). Positive SARS-Cov-2 test in a woman with COVID-19 at 22 days after hospital discharge: A case report. Journal of Traditional Chinese Medical Sciences, 7(4), 413–417.
Martín Enguix, D., Aguirre Rodríguez, J. C., Sánchez Cambronero, M., & Hidalgo Rodríguez, A. (2021, December 23). PCR for COVID-19 positive, then negative and again positive Reinfection at 55 days? Semergen.
Martines, R. B., Ritter, J. M., Matkovic, E., Gary, J., Bollweg, B. C., Bullock, H., … Estetter, L. (2020). Pathology and pathogenesis of SARS-CoV-2 associated with fatal coronavirus disease, united states. Emerging Infectious Diseases, 26(9), 2005–2015.
Ni, L., Ye, F., Chen, M.-L., Feng, Y., Deng, Y.-Q., Zhao, H., … Dong, C. (2020a). Characterization of anti-viral immunity in recovered individuals infected by SARS-CoV-2. MedRxiv, 2020.03.17.20036640.
Ni, L., Ye, F., Chen, M. L., Feng, Y., Deng, Y. Q., Zhao, H., … Dong, C. (2020b, March 20). Characterization of anti-viral immunity in recovered individuals infected by SARS-CoV-2. MedRxiv.
Párraga Martínez, I., Pérula de Torres, L. A., González Lama, J., Jiménez García, C., Sánchez Montero, R., & Rider Garrido, F. (2021). Clinical and epidemiological characteristics of SARS-CoV-2 infections in family physicians: A case-control study. Atencion Primaria, 53(3), 101956.
Parry, J. (2020). Covid-19: Hong Kong scientists report first confirmed case of reinfection. BMJ (Clinical Research Ed.), 370, m3340.
Pathangey, G., Fadadu, P. P., Hospodar, A. R., & Abbas, A. E. (2021). Angiotensin-converting enzyme 2 and COVID-19: Patients, comorbidities, and therapies. American Journal of Physiology - Lung Cellular and Molecular Physiology, 320(3), L301–L330.
Renu, K., Prasanna, P. L., & Valsala Gopalakrishnan, A. (2020, August 15). Coronaviruses pathogenesis, comorbidities and multi-organ damage – A review. Life Sciences, Vol. 255.
Rhee, C., Kanjilal, S., Baker, M., & Klompas, M. (2020). Duration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infectivity: When Is It Safe to Discontinue Isolation? Clinical Infectious Diseases.
Shastri, M. D., Shukla, S. D., Chong, W. C., KC, R., Dua, K., Patel, R. P., … O’Toole, R. F. (2021). Smoking and COVID-19: What we know so far. Respiratory Medicine, 176, 106237.
Tang, X., Musa, S. S., Zhao, S., Mei, S., & He, D. (2021). Using Proper Mean Generation Intervals in Modeling of COVID-19. Frontiers in Public Health, 9.
Telenti, A., Hodcroft, E. B., & Robertson, D. L. (2022). The Evolution and Biology of SARS-CoV-2 Variants. Cold Spring Harbor Perspectives in Medicine, a041390.
Tomassini, S., Kotecha, D., Bird, P. W., Folwell, A., Biju, S., & Tang, J. W. (2021). Setting the criteria for SARS-CoV-2 reinfection – six possible cases. Journal of Infection, 82(2), 282–327.
Uddin, M., Mustafa, F., Rizvi, T. A., Loney, T., Al Suwaidi, H., Al-Marzouqi, A. H. H., … Senok, A. C. (2020). SARS-CoV-2/COVID-19: Viral Genomics, Epidemiology, Vaccines, and Therapeutic Interventions. Viruses 2020, Vol. 12, Page 526, 12(5), 526.
Vibholm, L. K., Nielsen, S. S., Pahus, M. H., Frattari, G. S., Olesen, R., Andersen, R., … Tolstrup, M. (2021). SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses. EBioMedicine, 64, 103230.
Wang, C., Horby, P. W., Hayden, F. G., & Gao, G. F. (2020). A novel coronavirus outbreak of global health concern. The Lancet, 395(10223), 470–473.
Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., Cao, B. (2020a). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet, 395(10229), 1054–1062.
Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., Cao, B. (2020b). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet, 395(10229), 1054–1062.
Derechos de autor 2023 Marco Antonio Becerril Flores ;Eva María Molina Trinidad ;Enrique de Jesús Moreno López ;José Ramón Montejano Rodríguez;Antonio Santos Castañeda
Esta obra está bajo licencia internacional Creative Commons Reconocimiento 4.0.
.jpg)
