Evaluación de la relación entre los componentes del síndrome metabólico y la aparición y progresión del cáncer

Palabras clave: hipertensión, hiperglucemia, hipertrigliceridemia, obesidad abdominal, lipoproteins, IDL

Resumen

Introducción: El síndrome metabólico es una afección médica que se caracteriza por la presencia de varios factores de riesgo metabólicos, incluyendo obesidad, hipertensión arterial, resistencia a la insulina, dislipidemia y niveles elevados de glucosa en sangre. Estos factores de riesgo se han asociado con un mayor riesgo de desarrollar enfermedades cardiovasculares, diabetes tipo 2 y ciertos tipos de cáncer. Objetivo: El objetivo de esta revisión es evaluar la relación entre los componentes del síndrome metabólico y la aparición y progresión del cáncer.  Metodología: Para ello, se llevará a cabo una revisión bibliográfica exhaustiva para identificar estudios relevantes que hayan analizado la relación entre los componentes del síndrome metabólico y diferentes tipos de cáncer.  Conclusión: Los resultados de esta investigación podrían proporcionar una comprensión más profunda de la relación entre los componentes del síndrome metabólico y la aparición y progresión del cáncer.

Descargas

La descarga de datos todavía no está disponible.

Citas

Karra P, Winn M, Svenja Pauleck, Alicja Bulsiewicz-Jacobsen, Peterson L, Coletta AM, et al. Metabolic dysfunction and obesity‐related cancer: Beyond obesity and metabolic syndrome. 2022 Jul 1 [cited 2023 Jun 20];30(7):1323–34. https://doi.org/10.1002/oby.23444

Zhao P, Xia N, Zhang H, Deng T. The Metabolic Syndrome Is a Risk Factor for Breast Cancer: A Systematic Review and Meta-Analysis. 2020 Jan 1 [cited 2023 Jun 20];13(4):384–96. https://doi.org/10.1159/000507554

Yang X, Wang J. The Role of Metabolic Syndrome in Endometrial Cancer: A Review. 2019 Aug 8 [cited 2023 Jun 20];9. https://doi.org/10.3389/fonc.2019.00744

Ki Tae Hwang, Han K, Oh S, Bo Kyung Koo, Sender Herschorn, Kim J, et al. Influence of Metabolic Syndrome on Risk of Breast Cancer: A Study Analyzing Nationwide Data from Korean National Health Insurance Service. 2020 Oct 1 [cited 2023 Jun 20];29(10):2038–47. https://doi.org/10.1158/1055-9965.epi-20-0300

Lu B, Qian J, Li J-N. The metabolic syndrome and its components as prognostic factors in colorectal cancer: A meta‐analysis and systematic review. 2022 Nov 8 [cited 2023 Jun 20];38(2):187–96. https://doi.org/10.1111/jgh.16042

Seo J-H, Ho Y. K, Beum P. C, Han K, Hoon J. Y,. Hypertension is associated with oral, laryngeal, and esophageal cancer: a nationwide population-based study. 2020 Jun 24 [cited 2023 Jun 20];10(1). https://doi.org/10.1038/s41598-020-67329-3

Houng L. S., Hye Sun L. H., Bong L. S., Hun K. S., Nam S. K., Kyung J. H., et al. Clinical impact of pre-hypertension on the risk of cancer in male and female subjects. 2020 Jun 19 [cited 2023 Jun 20];10(1). https://doi.org/10.1038/s41598-020-66653-y

Han H, Guo W, Shi W, Yu Y, Zhang Y, Ye X, et al. Hypertension and breast cancer risk: a systematic review and meta-analysis. 2018 Mar 20 [cited 2023 Jun 20];7(1). https://doi.org/10.1038/srep44877

Katherine, Shin W-K, Huang D, Lee H-W, Shin M-H, Lee J-K, et al. Mildly elevated diastolic blood pressure increases subsequent risk of breast cancer in postmenopausal women in the Health Examinees-Gem study. 2022 Sep 26 [cited 2023 Jun 20];12(1). https://doi.org/10.1038/s41598-022-19705-4

Feng W, Guo H, Gong H, Xue T, Wang X, Tang C, et al. Comprehensive transcriptome analysis of colorectal cancer risk of hyperglycemia in humans. 2021 Apr 1 [cited 2023 Jun 20];12(2):602–19. https://doi.org/10.21037/jgo-20-587

Marrone MJ, Selvin E, Barber JCK, Platz EA, Joshu CE. Hyperglycemia, Classified with Multiple Biomarkers Simultaneously in Men without Diabetes, and Risk of Fatal Prostate Cancer. 2019 Feb 1 [cited 2023 Jun 20];12(2):103–12. https://doi.org/10.1158/1940-6207.capr-18-0216

Gutiérrez-Gutiérrez M, Figueroa-Martínez IA, Jurado R, Uribe N, García-López P, Rojas JMP. Hyperglycemia and hyperinsulinemia stimulate cervical cancer cell proliferation in vitro and in vivo study. 2019 Dec 12 [cited 2023 Jun 20]; https://doi.org/10.21203/rs.2.18710/v1

Aaron‐Brooks LM, Sasaki T, Vickman RE, Wei L, Franco OE, Ji Y, et al. Hyperglycemia and T Cell infiltration are associated with stromal and epithelial prostatic hyperplasia in the nonobese diabetic mouse. 2019 Apr 18 [cited 2023 Jun 20];79(9):980–93. https://doi.org/10.1002/pros.23809

Hsu S-H, De-Kai Syu, Chen Y-C, Liu C-K, Sun C-A, Chen M. The Association between Hypertriglyceridemia and Colorectal Cancer: A Long-Term Community Cohort Study in Taiwan. 2022 Jun 25 [cited 2023 Jun 20];19(13):7804–4. https://doi.org/10.3390/ijerph19137804

Wan Y, Zhang J, Chen M, Ma M, Sheng B. Hypertriglyceridemia May be a Key Independent Predicting Factor for Gallbladder Cancer Risk in Gallbladder Stone Disease Patients: A Case-Control Study. 2022 Mar 15 [cited 2023 Jun 20]; https://doi.org/10.21203/rs.3.rs-1448209/v1

Hernández-P. J, Torres S. L., HernándezA. C., López C. L, Rodríguez C. F, Argelia V., et al. Metabolic Syndrome and Prostate Cancer Risk: A Population Case-control Study. 2022 Sep 1 [cited 2023 Jun 20];53(6):594–602. https://doi.org/10.1016/j.arcmed.2022.07.003

Tavakoli A, Khadijeh Mirzaei, Moosavi H, Sanaz Mehranfar, Seyed Ali Keshavarz, Khadijeh Mirzaei. Dietary inflammatory index (DII) may be associated with hypertriglyceridemia waist circumference phenotype in overweight and obese Iranian women: a cross sectional study. 2021 Aug 16 [cited 2023 Jun 20];14(1). https://doi.org/10.1186/s13104-021-05712-7

Vanegas DP, Ramírez López LX, Limas Solano LM, Pedraza Bernal AM, Monroy Díaz AL. Revisión: Factores asociados a cáncer colorrectal. Revista Médica de Risaralda [Internet]. 2020 Jun 30;26(1). https://doi.org/10.22517/25395203.23111

Cruz JC, Guzmán A, Angélica López, Napoleón Navarro Tito. OBESIDAD Y CÁNCER DE MAMA: UNA RELACIÓN ENTRE EPIDEMIAS MODERNAS. 2018 Dec 23 [cited 2023 Jun 21]; https://doi.org/10.18633/biotecnia.v21i1.814

Torres-Lobatón A, Barra-Martínez R, Elisa Paola Jiménez-Arroyo, Jesús Portillo-Reyes, Carla América Suárez-Juárez, Morgan-Ortiz F. Obesidad y cáncer de endometrio: las repercusiones de un problema de salud pública. Ginecología y Obstetricia de México [Internet]. 2020 Sep 22 [cited 2023 Jun 21];88(09):569–74.

Cedó L, Reddy ST, Mato E, Blanco-Vaca F, Escolà-Gil JC. HDL and LDL: Potential New Players in Breast Cancer Development. J Clin Med. junio de 2019;8(6):853. https://doi.org/10.3390/jcm8060853

Loosen SH, Kostev K, Luedde M, Luedde T, Roderburg C. Low blood levels of high-density lipoprotein (HDL) cholesterol are positively associated with cancer. J Cancer Res Clin Oncol. 1 de noviembre de 2022;148(11):3039–46. https://doi.org/10.1007/s00432-021-03867-1

Crocetto F, Pandolfo SD, Aveta A, Martino R, Trama F, Caputo VF, et al. A Comparative Study of the Triglycerides/HDL Ratio and Pseudocholinesterase Levels in Patients with Bladder Cancer. Diagnostics. febrero de 2022;12(2):431. https://doi.org/10.3390/diagnostics12020431

Pih GY, Gong EJ, Choi JY, Kim MJ, Ahn JY, Choe J, et al. Associations of Serum Lipid Level with Gastric Cancer Risk, Pathology, and Prognosis. Cancer Res Treat. abril de 2021;53(2):445–56. https://doi.org/10.4143/crt.2020.599

Zhang Y, Song M, Chan AT, Meyerhardt JA, Willett WC, Giovannucci E. Long-term use of antihypertensive medications, hypertension and colorectal cancer risk and mortality: a prospective cohort study. 2022; 127(11):1974–82. https://doi.org/10.1038/s41416-022-01975-4

Seretis A, Cividini S, Markozannes G, Tseretopoulou X, Lopez DS, Ntzani EE, et al. Association between blood pressure and risk of cancer development: a systematic review and meta-analysis of observational studies. Scientific Reports [Internet]. 2019 Jun 12 [cited 2023 Apr 10];9(1). https://doi.org/10.1038/s41598-019-45014-4

Liang Z, Xie B, Li J, Wang X, Wang S, Meng S, et al. Hypertension and risk of prostate cancer: a systematic review and meta-analysis. Scientific Reports [Internet]. 2016 Aug 11 [cited 2023 Apr 10];6(1). https://doi.org/10.1038/srep31358

Zhong A, Chen Y, Phang Lang Chen. Diabetes-Cancer Risk: Hyperglycemia on DNA Damage and Repair. American Journal of Biomedical Science & Research [Internet]. 2019 Oct 10 [cited 2023 Jun 20];5(4):334-.https://doi.org/10.34297/AJBSR.2019.05.000939

Da Young Lee, Taek Seung Lee. Associations between metabolic syndrome and gynecologic cancer. 2020 May 15 [cited 2023 Jun 20];63(3):215–24. https://doi.org/10.5468/ogs.2020.63.3.215

Li W, Wang Z, Xiao X, Han L, Wu Z, Ma Q, et al. Curcumin attenuates hyperglycemia-driven EGF-induced invasive and migratory abilities of pancreatic cancer via suppression of the ERK and AKT pathways. 2018 Oct 30 [cited 2023 Jun 20]; https://doi.org/10.3892/or.2018.6833

Xu X, Chen B, Zhu S, Zhang J, He X, Cao G, et al. Hyperglycemia promotes Snail-induced epithelial–mesenchymal transition of gastric cancer via activating ENO1 expression. 2019 Dec 1 [cited 2023 Jun 20];19(1). https://doi.org/10.1186/s12935-019-1075-8

Justyna Dłubek, Rysz J, Zbigniew Jabłonowski, Gluba-Brzózka A, Franczyk B. The Correlation between Lipid Metabolism Disorders and Prostate Cancer. 2021 Mar 1 [cited 2023 Jun 20];28(10):2048–61. https://doi.org/10.2174/0929867327666200806103744

Sun J, Lou Y, Zhu J-J, Shen H, Zhou D, Zhu L, et al. Hypertriglyceridemia in Newly Diagnosed Acute Promyelocytic Leukemia. 2020 Nov 25 [cited 2023 Jun 20];10. https://doi.org/10.3389/fonc.2020.577796

Satoru Mitsuboshi, Takahiro Niimura, Yoshino M, Sakamoto Y, Yoshito Zamami, Keisuke Ishizawa. Fluoropyridmidine use and hypertriglyceridemia among Japanese patients: analysis of adverse event database. 2021 Sep 5 [cited 2023 Jun 20];44(1):260–3. https://doi.org/10.1007/s11096-021-01324-0

Nancy Molano Tobar, Felipe A, Ximena D. Índices de obesidad en mujeres con cáncer de mama del Cauca, Colombia. MHSalud: Movimiento Humano y Salud [Internet]. 2023 [cited 2023 Jun 21];20(1):7. https://dialnet.unirioja.es/descarga/articulo/8734753.pdf

Yosbani Cedeño Yera, Fonseca L, David E. Impacto de la obesidad en la agresividad del cáncer de próstata. MULTIMED [Internet]. 2021 [cited 2023 Jun 21];25(3).

Publicado
2023-07-06
Cómo citar
Villa Clavijo , C. G., Mendez Guerrero, J. A., Tsenkush Chamik , E. R., Alvarracin Chocho , L. J., Sarmiento Sarmiento , C. E., & Aponte Cisneros , K. N. (2023). Evaluación de la relación entre los componentes del síndrome metabólico y la aparición y progresión del cáncer. Ciencia Latina Revista Científica Multidisciplinar, 7(3), 7111-7123. https://doi.org/10.37811/cl_rcm.v7i3.6701
Sección
Artículos

Artículos más leídos del mismo autor/a