Cold Radiofrequency Ablation for Vertebral Bone Tumors: OsteoCool, Case Report and Literature Review

Palabras clave: cold radiofrequency, bone tumors, benign tumors, metastases, spinal cord

Resumen

Background: The spine is the most frequently affected site in skeletal metastases, representing up to 70% of cases. These lesions can cause severe pain, fractures, and neurological deficits, significantly affecting quality of life. Conventional management includes opioids, bisphosphonates, surgery, and radiotherapy; however, these may be limited by delayed recovery, toxicity, or long-term side effects. Case presentation: We describe the case of a 38-year-old male with a vertebral lesion at T6, suggestive of metastasis, who underwent percutaneous cold radiofrequency ablation using the OsteoCool system combined with kyphoplasty. The procedure was completed without complications, achieving immediate pain relief and early mobilization, allowing hospital discharge within 24 hours. Discussion: Cold radiofrequency ablation offers a safe, minimally invasive alternative for the treatment of vertebral bone tumors, providing rapid pain control, reduced opioid use, and early initiation of adjuvant therapies. Conclusion: In selected patients, OsteoCool radiofrequency ablation can improve prognosis and quality of life, representing an effective option in both palliative and curative settings.

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Torres-castaño, A., Rivero-Santana, A., Perestelo-Pérez, L., Toledo-chávarri, A., Duarte-Diaz, A., Alvarez-Perez, Y., … Serrano-Aguilar, P. (2021). PP126 Radiofrequency Ablation For Metastatic Spinal Lesions. International Journal of Technology Assessment in Health Care, 37(S1), 20–21. doi:10.1017/S0266462321001161

David, E., Kaduri, S., Yee, A., Chow, E., Sahgal, A., Chan, S., & Hanna, R. (2017). Initial single center experience: radiofrequency ablation assisted vertebroplasty and osteoplasty using a bipolar device in the palliation of bone metastases. Annals of palliative medicine, 6(2), 118–124. https://doi.org/10.21037/apm.2016.12.02

Pezeshki, P. S., Woo, J., Akens, M. K., Davies, J. E., Gofeld, M., Whyne, C. M., & Yee, A. J. (2014). Evaluation of a bipolar-cooled radiofrequency device for ablation of bone metastases: preclinical assessment in porcine vertebrae. The spine journal : official journal of the North American Spine Society, 14(2), 361–370. https://doi.org/10.1016/j.spinee.2013.08.041

Sunenshine, P. (2020). Radiofrequency Ablation for the Palliative Treatment of Bone Metastases: Outcomes from the Multicenter OsteoCool Tumor Ablation Post-Market Study (OPuS One Study) in 100 Patients. Journal of Vascular and Interventional Radiology.

https://doi.org/10.1016/J.JVIR.2020.07.014

Levy, J., David, E., Hopkins, T., Morris, J., Tran, N. D., Farid, H., Massari, F., O'Connell, W. G., Vogel, A., Gangi, A., Sunenshine, P., Dixon, R., Von der Höh, N., & Bagla, S. (2023). Radiofrequency Ablation Provides Rapid and Durable Pain Relief for the Palliative Treatment of Lytic Bone Metastases Independent of Radiation Therapy: Final Results from the OsteoCool Tumor Ablation Post-Market Study. Cardiovascular and interventional radiology, 46(5), 600–609. https://doi.org/10.1007/s00270-023-03417-x

Agila Mocha, R. J., Vivanco Ureña, C. I., León Bravo, F. E., & Reyes Carrión , J. P. (2025). Software Educativos para el Proceso de Enseñanza Aprendizaje de Matemáticas en Bachillerato. Ciencia Y Reflexión, 4(2), 1341–1369. https://doi.org/10.70747/cr.v4i2.334

Urquidez Romero , R., Avitia Sánchez, A., Cano Ramírez , D., Jiménez Montes , L. V., Barranco Merino, G. I., & Reyes Ruvalcaba, D. (2025). Programa de Intervención con un Suplemento Multivitamínico para Mejorar el Estado de Nutrición y Anemia en Niños en Condición de Vulnerabilidad Social de Ciudad Juárez Chihuahua. Ciencia Latina Revista Científica Multidisciplinar, 9(3), 8340-8354. https://doi.org/10.37811/cl_rcm.v9i3.18460

Añapa Quiñónez, P. L., Recalde Páez, J. P., Fey Zalamea, C. D., Rivera Quiñónez, E. D., & Acuri Pacheco, D. A. (2025). Estrategias para la Implementación Efectiva del Aprendizaje Híbrido (Blended Learning) en Instituciones Educativas Rurales del Ecuador: Un Análisis Integral. Ciencia Y Reflexión, 4(2), 1160–1184. https://doi.org/10.70747/cr.v4i2.325

Tenesaca Canchignia , D. C., Canchignia Bonilla, E. L., Remache Guamán, N. V., Guamán Sagñay , H. P., & Hualcopo Duchicela, U. E. (2025). Guía para padres con respecto al uso de dispositivos móviles el niños de nivel preparatorio. Arandu UTIC, 12(2), 287–307. https://doi.org/10.69639/arandu.v12i2.925

Araujo García, D., Chang Espinosa , O. Y., & Pérez Vázquez , D. (2025). Consultoría Estratégica para Mipymes: Estudio de Mercado para Impulsar el Desarrollo Regional en Perote, Veracruz. Estudios Y Perspectivas Revista Científica Y Académica , 5(3), 27–45. https://doi.org/10.61384/r.c.a.v5i3.1328

Simbaña Cabrera, H. A., Haro Jácome, O. F., García-Romero , C. A., & Analuisa García , P. S. (2025). La titulación rural, una propuesta colectiva que evidencia la realidad educativa de las escuelas multigrado. Emergentes - Revista Científica, 5(2), 1–14. https://doi.org/10.60112/erc.v5.i2.385

Cortés Viveros, N., Hernández García, R. A., Galván Sarabia, A., Olivares Galvan, H. R., & Texon Olguin, O. A. (2025). En Busca del Modelo Ideal para Determinar las Variables que Explican el Tiempo de Desempleo en Buscadores Xalapeños. Estudios Y Perspectivas Revista Científica Y Académica , 5(3), 65–81. https://doi.org/10.61384/r.c.a.v5i3.1332

Bernal Parraga, A. P., Salazar Véliz , E. T., Zambrano Lamilla, L. M., Espinoza Jaramillo , S. G., Morales García , C. S., Shinger Hipatia, N. S., & Zapata Calderón , S. J. (2025). Innovaciones Didácticas para Lengua y Literatura Basadas en el Aprendizaje Personalizado y Colaborativo . Revista Científica De Salud Y Desarrollo Humano , 6(2), 01–32. https://doi.org/10.61368/r.s.d.h.v6i2.574

Sabando Suárez, A. A., Vega Guamangate, J. M., García Gallirgos, V. J., & Mora Carpio, W. T. (2025). Impacto del Gasto Social en el Índice de Desarrollo Humano en Ecuador. periodo 2001-2023. Revista Veritas De Difusão Científica, 6(2), 1593–1633. https://doi.org/10.61616/rvdc.v6i2.707

Jain, S., Kinch, L., Rana, M., & Anitescu, M. (2020). Comparison of post-operative pain scores and opioid use between kyphoplasty and radiofrequency ablation (RFA) systems combined with cement augmentation. Skeletal radiology, 49(11), 1789–1794

https://doi.org/10.1007/s00256-020-03473-1

Angileri, S. A., Granata, G., Savoldi, A. P., Rodà, G. M., Di Meglio, L., Grillo, P., Tortora, S., Arrichiello, A., Papa, M., Liguori, A., Ierardi, A. M., De Filippo, M., Paolucci, A., & Carrafiello, G. (2020). Cooled radiofrequency ablation technology for painful bone tumors. Acta bio-medica : Atenei Parmensis, 91(10-S), e2020007.

https://doi.org/10.23750/abm.v91i10-S.10271

Cerny, J., Soukup, J., Cerna, S., & Novotny, T. (2022). Current Approaches to Osteoid Osteoma and Minimally Invasive Surgery-A Minireview and a Case Report. Journal of clinical medicine, 11(19), 5806. https://doi.org/10.3390/jcm11195806

S. Bagla, S.Bolstrom,.(2020) OPuS One trial: a postmarket study to evaluate the effectiveness of the OsteoCoolTM Radiofrequency (RF) Ablation System, Journal of Vascular and Interventional Radiology. doi:10.1016/j.jvir.2018.01.535

Levy, J., Bagla. S.(2022). Palliative treatment of pelvic bone metastases with radiofrequency ablation: an OPuS One sub-analysis. Journal of Vascular and Interventional Radiology. doi:10.1016/j.jvir.2022.03.526

Levy, J., David, E., Hopkins. (2021) Improvement in quality of life in patients treated for painful osseous metastases with radiofrequency ablation: the OPuS one study, Journal of Vascular and Interventional Radiology. doi:10.1016/j.jvir.2021.03.501

Levy, J., David, E., Hopkins, T., Morris, J., Tran, N. D., Farid, H., Massari, F., O'Connell, W. G., Vogel, A., Gangi, A., Sunenshine, P., Dixon, R., Von der Höh, N., & Bagla, S. (2023). Radiofrequency Ablation Provides Rapid and Durable Pain Relief for the Palliative Treatment of Lytic Bone Metastases Independent of Radiation Therapy: Final Results from the OsteoCool Tumor Ablation Post-Market Study. Cardiovascular and interventional radiology, 46(5), 600–609. https://doi.org/10.1007/s00270-023-03417-x

Jain, S., Kinch, L., Rana, M., & Anitescu, M. (2020). Comparison of post-operative pain scores and opioid use between kyphoplasty and radiofrequency ablation (RFA) systems combined with cement augmentation. Skeletal radiology, 49(11), 1789–1794.

https://doi.org/10.1007/s00256-020-03473-1

Cerny, J., Soukup, J., Cerna, S., & Novotny, T. (2022). Current Approaches to Osteoid Osteoma and Minimally Invasive Surgery-A Minireview and a Case Report. Journal of clinical medicine, 11(19), 5806. https://doi.org/10.3390/jcm11195806

Publicado
2025-10-14
Cómo citar
Hernandez Vargas , U., De La Paz Ponce, Y. G., Martinez Zeron, V., Gomez Pimentel, P., Barker Antonio, A., Diaz de Jesus, B., & Alvaro Heredia, J. A. (2025). Cold Radiofrequency Ablation for Vertebral Bone Tumors: OsteoCool, Case Report and Literature Review. Ciencia Latina Revista Científica Multidisciplinar, 9(4), 11914-11923. https://doi.org/10.37811/cl_rcm.v9i4.19904
Sección
Ciencias de la Salud

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