Evento cerebrovascular en pacientes post COVID-19

Palabras clave: SARS-CoV-2, COVID-19, Stroke, Neurological, Long-Term

Resumen

Objetivo: El presente estudio pretende determinar la asociación y factores implicados entre haber padecido un evento de COVID-19 con el desarrollo de un evento cerebrovascular. Métodos: Es un estudio observacional, de casos y controles, analítico, retrospectivo, con relación 1:2. Aplicado en la población del servicio de Urgencias, Medicina interna y Medicina familiar, del Hospital General de Zona con Medicina Familiar N° 32 de Minatitlán Veracruz. Resultados: Se obtuvo una muestra final de 111 casos y 222 controles. El promedio de edad es de 58 años ±17.6. Del total de pacientes 126 (37.8%) son hombres y 207 (62.2%) son mujeres. 159 pacientes (47.74%) tuvieron antecedente positivo de COVID-19. Se encontró un Odds Ratio de 1.38 (95%; 0.876 – 2.186). La edad de los pacientes, la gravedad de la infección en su fase aguda, el nivel de gravedad del evento cerebrovascular y el antecedente de vacuna, fueron resultados estadísticamente significativos. Conclusión: El COVID-19 se encuentra asociado como factor independiente al desarrollo de evento cerebrovascular.

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Shaw B, Daskareh M, Gholamrezanezhad A. The lingering manifestations of COVID-19 during and after convalescence: update on long-term pulmonary consequences of coronavirus disease 2019 (COVID-19). Radiol Med. 2021;126(1):40-46. doi: 10.1007/s11547-020-01295-8.

Secretaria de Salud, Direccion General de Epidemiologia. 31° Informe epidemiológico de la situación de COVID-19, 2021 [online]. Disponible en: https://www.gob.mx/cms/uploads/attachment/file/668356/Informe_COVID-19_2021.09.13.pdf [consultado el 12.09.2021]

Suárez, V., Suarez Quezada, M., Oros Ruiz, S., Ronquillo De Jesús, E. Epidemiología de COVID-19 en México: del 27 de febrero al 30 de abril de 2020. Rev Clin Esp. 2020;220(8):463–471. https://doi.org/10.1016/j.rce.2020.05.007

Secretaria de Salud, Direccion General de Epidemiologia. Boletín Epidemiológico semanal número 35, volumen 38, 2021 [online]. Disponible en: https://www.gob.mx/cms/uploads/attachment/file/693152/sem35.pdf [consultado el 12.09.2021].

Wiersinga WJ, Rhodes A, Cheng AC, et al. Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review. JAMA. 2020;324(8):782-793. doi: 10.1001/jama.2020.12839.

Leung TYM, Chan AYL, Chan EW, et al. Short- and potential long-term adverse health outcomes of COVID-19: a rapid review. Emerg Microbes Infect. 2020;9(1):2190-2199. doi: 10.1080/22221751.2020.1825914.

Arévalos V, Ortega-Paz L, Fernandez-Rodríguez D, et al. Long-term effects of coronavirus disease 2019 on the cardiovascular system, CV COVID registry: A structured summary of a study protocol. PLoS One. 2021;16(7): e0255263. doi: 10.1371/journal.pone.0255263.

Kamal M, Abo Omirah M, Hussein A, Saeed H. Assessment, and characterisation of post-COVID-19 manifestations. Int J Clin Pract. 2021;75(3):e13746. doi: 10.1111/ijcp.13746.

Heneka MT, Golenbock D, Latz E, Morgan D, Brown R. Immediate and long-term consequences of COVID-19 infections for the development of neurological disease. Alzheimers Res Ther. 2020;12(1):69. doi: 10.1186/s13195-020-00640-3.

Carroll E, Neumann H, Aguero-Rosenfeld ME, et al. Post-COVID-19 inflammatory syndrome manifesting as refractory status epilepticus. Epilepsia. 2020;61(10):e135-e139. doi: 10.1111/epi.16683.

Brundin P, Nath A, Beckham JD. Is COVID-19 a Perfect Storm for Parkinson's Disease? Trends Neurosci. 2020;43(12):931-933. doi: 10.1016/j.tins.2020.10.009.

Ellul MA, Benjamin L, Singh B, et al. Neurological associations of COVID-19. Lancet Neurol. 2020;19(9):767-783. doi: 10.1016/S1474-4422(20)30221-0.

Elfasi A, Echevarria FD, Rodriguez R, et al. Impact of COVID-19 on Future Ischemic Stroke Incidence. eNeurologicalSci. 2021; 22:100325. doi: 10.1016/j.ensci.2021.100325.

Merkler AE, Parikh NS, Mir S, et al. Risk of Ischemic Stroke in Patients with Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza. JAMA Neurol. 2020;77(11):1366–1372. doi:10.1001/jamaneurol.2020.2730

Elkind MSV, Boehme AK, Smith CJ, Meisel A, Buckwalter MS. Infection as a Stroke Risk Factor and Determinant of Outcome After Stroke. Stroke. 2020;51(10):3156-3168. doi:10.1161/strokeaha.120.030429.

Ayoubkhani D, Khunti K, Nafilyan V, et al. Post-covid syndrome in individuals admitted to hospital with covid-19: retrospective cohort study. BMJ. 2021;372:n693. doi: 10.1136/bmj.n693.

Xie, Y., Xu, E., Bowe, B. et al. Long-term cardiovascular outcomes of COVID-19. Nat Med. 2022;28:583–590. https://doi.org/10.1038/s41591-022-01689-3

Tu TM, Seet CYH, Koh JS, et al. Acute Ischemic Stroke During the Convalescent Phase of Asymptomatic COVID-2019 Infection in Men. JAMA Netw Open. 2021 ;4(4) : e217498. doi: 10.1001/jamanetworkopen.2021.7498.

Mafham M, Baigent C. What is the association of COVID-19 with heart attacks and strokes? Lancet. 2021;398(10300):561-563. doi: 10.1016/S0140-6736(21)01071-0.

Pinzon RT, Kumalasari MD, Kristina H. Ischemic Stroke following COVID-19 in a Patient without Comorbidities. Case Rep Med. 2021; 2021:8178529. doi: 10.1155/2021/8178529.

Ojo AS, Balogun SA, Idowu AO. Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management. Neurol Res Int. 2020;2020:7397480. doi: 10.1155/2020/7397480.

Akhtar N, Abid F, Singh R, et al. Ischemic stroke in patients that recover from COVID-19: Comparisons to historical stroke prior to COVID-19 or stroke in patients with active COVID-19 infection. PLoS One. 2022;17(6):e0270413. doi: 10.1371/journal.pone.0270413.

Nannoni S, de Groot R, Bell S, Markus HS. Stroke in COVID-19: A systematic review and meta-analysis. Int J Stroke. 2021;16(2):137-149. doi: 10.1177/1747493020972922.

Perry RJ, Smith CJ, Roffe C, et al. Characteristics and outcomes of COVID-19 associated stroke: a UK multicentre case-control study. J Neurol Neurosurg Psychiatry. 2021;92(3):242-248. doi: 10.1136/jnnp-2020-324927.

Jabbour P, Dmytriw AA, Sweid A, et al. Characteristics of a COVID-19 Cohort With Large Vessel Occlusion: A Multicenter International Study. Neurosurgery. 2022;90(6):725-733. doi: 10.1227/neu.0000000000001902.

Ruiz-Ares G, Jimenez-Valero S, Fernández-Prieto et al. Concurrent Stroke and Myocardial Infarction After Mild COVID-19 Infection. Neurologist. 2021;26(3):86-89. doi: 10.1097/NRL.0000000000000311.

Nakanishi T, Pigazzini S, Degenhardt F, et al. Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. J Clin Invest. 2021;131(23): e152386. doi: 10.1172/JCI152386.

Fifi JT, Mocco J. COVID-19 related stroke in young individuals. Lancet Neurol. 2020;19(9):713-715. doi: 10.1016/S1474-4422(20)30272-6.

Luo W, Liu X, Bao K, Huang C. Ischemic stroke associated with COVID-19: a systematic review and meta-analysis. J Neurol. 2022;269(4):1731-1740. doi: 10.1007/s00415-021-10837-7

Michela Antonelli, Rose S Penfold, Jordi Merino, et al. Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study. Lancet. 2022;22(1)43-55. https://doi.org/10.1016/S1473-3099(21)00460-6

Al-Aly Z, Bowe B, Xie Y. Long COVID after breakthrough SARS-CoV-2 infection. Nat Med. 2022;28(7):1461-1467. doi: 10.1038/s41591-022-01840-0.

Huang C, Huang L, Wang Y, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet. 2021;397(10270):220-232. doi: 10.1016/S0140-6736(20)32656-8.

Lopez-Leon S, Wegman-Ostrosky T, Perelman C, et al. More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis. medRxiv [Preprint]. 2021:2021.01.27.21250617. doi: 10.1101/2021.01.27.21250617

Varela Rodríguez C, Arias Horcajadas F, Martín-Arriscado Arroba C, et al. COVID-19-Related Neuropsychiatric Symptoms in Patients With Alcohol Abuse Conditions During the SARS-CoV-2 Pandemic: A Retrospective Cohort Study Using Real World Data From Electronic Health Records of a Tertiary Hospital. Front Neurol. 2021; 12:630566. doi: 10.3389/fneur.2021.630566.

Baker J, Krishnan N, Abroms LC, Berg CJ. The Impact of Tobacco Use on COVID-19 Outcomes: A Systematic Review. J Smok Cessat. 2022; 2022:5474397. doi: 10.1155/2022/5474397

Archie SR, Cucullo L. Cerebrovascular and Neurological Dysfunction under the Threat of COVID-19: Is There a Comorbid Role for Smoking and Vaping? Int J Mol Sci. 2020;21(11):3916. doi: 10.3390/ijms21113916

Qureshi AI, Baskett WI, Huang W, et al. Acute Ischemic Stroke and COVID-19: An Analysis of 27 676 Patients. Stroke. 2021;52(3):905-912. doi: 10.1161/strokeaha.120.031786

Al-Kuraishy HM, Al-Gareeb AI, Alblihed M, Cruz-Martins N, Batiha GE. COVID-19 and Risk of Acute Ischemic Stroke and Acute Lung Injury in Patients With Type II Diabetes Mellitus: The Anti-inflammatory Role of Metformin. Front Med (Lausanne). 2021; 8:644295. doi: 10.3389/fmed.2021.644295

Belani P, Schefflein J, Kihira S, et al. COVID-19 Is an Independent Risk Factor for Acute Ischemic Stroke. AJNR Am J Neuroradiol. 2020;41(8):1361-1364. doi: 10.3174/ajnr. A6650

Publicado
2022-11-08
Cómo citar
Hernández Moreno, J. E., Cruz Herrera, J., Hernandez , E. L., Pérez Parrilla, V. M., Rodríguez Guzmán, L. M., & Puig Lagunes , Ángel A. (2022). Evento cerebrovascular en pacientes post COVID-19. Ciencia Latina Revista Científica Multidisciplinar, 6(5), 4046-4069. https://doi.org/10.37811/cl_rcm.v6i5.3374
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