Pleiotropy and Phenotypic Plasticity: Exploring the Correlation between Cognitive Traits and Craniofacial Morphology Throughout Human Development
Palabras clave:
high iq, phenotypic changes, behavioral genetics, neurodevelopment, phenotypic plasticity
Resumen
This study investigates the hypothesis that individuals with a high intelligence quotient (IQ) experience more significant phenotypic changes throughout their lives compared to the general population. Using a sample of 40 high-IQ individuals from the Gifted Debate group, this study analyzed self-reports of physical changes from childhood to adulthood. The majority of participants (90%) reported substantial alterations, while the remaining 10%, diagnosed with twice-exceptionality, may not have distinct perceptions of their phenotypic changes. The analysis focused on the correlation between high IQ and phenotypic plasticity, exploring potential genetic bases for these changes.
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Citas
BEATTY, J.; LUCERO-WAGONER, B. The pupillary system. In: CACIOPPO, J. T.; TASSINARY, L. G.; BERNTSon, G. (Eds.). Handbook of Psychophysiology. Cambridge: Cambridge University Press, p. 142-162, 2000.
COLE, J. B.; MANYAMA, M.; LARSON, J. R.; LIBERTON, D.; FERRARA, T.; RICCARDI, S. L.; LI, M.; MIO, W.; KLEIN, O.; SANTORICO, S. A.; HALLGRÍMSSON, B.; SPRITZ, R. Human Facial Shape and Size Heritability and Genetic Correlations. Genetics, v. 205, p. 967-978, 2016.
FERGUSON, J. N.; ALDENKAMP, B.; ROSSDALE, M. The Genetic Basis of Oxytocin Influence on Social Behavior: Implications for Understanding Visual Perception in Neuropsychiatric Disorders. Neuroendocrinology, v. 106, p. 89-101, 2018.
HILL, W. D.; MARIONI, R. E.; MAGHZIAN, O.; et al. A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. Molecular Psychiatry, v. 24, p. 169-181, 2018.
JOHNSON, D.; MORRISON, N.; GRANT, L. et al. GLI3 Transcriptional Factors and the Regulation of Cognition and Facial Development: Implications from Experimental and Clinical Studies. Brain Research Bulletin, v. 82, p. 320-330, 2010.
JONES, B. C.; LITTLE, A. C.; PENTON-VOAK, I. S.; TIDDEMAN, B. P.; BURT, D. M.; PERRETT, D. I. Facial symmetry and judgements of apparent health: Support for a “good genes” explanation of the attractiveness–symmetry relationship. Evolution and Human Behavior, v. 22, p. 417-429, 2001.
JUNG, R. E.; HAIER, R. J. The parieto-frontal integration theory (P-FIT) of intelligence: Converging neuroimaging evidence. Behavioral and Brain Sciences, v. 30, p. 135-154, 2007.
LIU, F.; VAN DEN BROEK, M.; SCHELTENS, P. et al. A Genome-wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans. Nature Genetics, v. 41, p. 1038-1042, 2009.
MITCHELL, K. J.; PINES, J.; HAMER, D. The genetics of eye development and function. Nature Reviews Genetics, v. 13, n. 6, p. 223-236, 2012.
MITCHELL, K. J.; PINTO, L.; RICHARDS, L. J. Regulation of Neuronogenesis and Eye Development by Pax6 Gene. Developmental Neuroscience, v. 34, p. 403-414, 2012.
RAYNER, K. Eye movements in reading and information processing: 20 years of research. Psychological Bulletin, v. 124, n. 3, p. 372-422, 1998.
ROESSLER, E.; MITTLEMAN, G.; MOSSER, J. A.; BELLONI, E. Role of the sonic hedgehog protein in the development of the human brain and face. Pediatric Research, v. 63, n. 4, p. 445-449, 2008.
SAVAGE, J. E.; JANSEN, P. R.; STRINGER, S.; et al. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics, v. 50, p. 912-919, 2018.
TOGA, A. W.; THOMPSON, P. M. Genetics of brain structure and intelligence. Annual Review of Neuroscience, v. 28, p. 1-23, 2005.
TWIGG, S. R. F.; WILKIE, A. O. M. New insights into craniofacial malformations. Human Molecular Genetics, v. 24, R1, p. R50-R59, 2015.
ZHANG, L.; HUANG, Y.; HONG, S. et al. Pax6 Plays a Role in the Development of the Eyes and Nasal Structures. Developmental Biology, v. 333, p. 156-166, 2011.
COLE, J. B.; MANYAMA, M.; LARSON, J. R.; LIBERTON, D.; FERRARA, T.; RICCARDI, S. L.; LI, M.; MIO, W.; KLEIN, O.; SANTORICO, S. A.; HALLGRÍMSSON, B.; SPRITZ, R. Human Facial Shape and Size Heritability and Genetic Correlations. Genetics, v. 205, p. 967-978, 2016.
FERGUSON, J. N.; ALDENKAMP, B.; ROSSDALE, M. The Genetic Basis of Oxytocin Influence on Social Behavior: Implications for Understanding Visual Perception in Neuropsychiatric Disorders. Neuroendocrinology, v. 106, p. 89-101, 2018.
HILL, W. D.; MARIONI, R. E.; MAGHZIAN, O.; et al. A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. Molecular Psychiatry, v. 24, p. 169-181, 2018.
JOHNSON, D.; MORRISON, N.; GRANT, L. et al. GLI3 Transcriptional Factors and the Regulation of Cognition and Facial Development: Implications from Experimental and Clinical Studies. Brain Research Bulletin, v. 82, p. 320-330, 2010.
JONES, B. C.; LITTLE, A. C.; PENTON-VOAK, I. S.; TIDDEMAN, B. P.; BURT, D. M.; PERRETT, D. I. Facial symmetry and judgements of apparent health: Support for a “good genes” explanation of the attractiveness–symmetry relationship. Evolution and Human Behavior, v. 22, p. 417-429, 2001.
JUNG, R. E.; HAIER, R. J. The parieto-frontal integration theory (P-FIT) of intelligence: Converging neuroimaging evidence. Behavioral and Brain Sciences, v. 30, p. 135-154, 2007.
LIU, F.; VAN DEN BROEK, M.; SCHELTENS, P. et al. A Genome-wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans. Nature Genetics, v. 41, p. 1038-1042, 2009.
MITCHELL, K. J.; PINES, J.; HAMER, D. The genetics of eye development and function. Nature Reviews Genetics, v. 13, n. 6, p. 223-236, 2012.
MITCHELL, K. J.; PINTO, L.; RICHARDS, L. J. Regulation of Neuronogenesis and Eye Development by Pax6 Gene. Developmental Neuroscience, v. 34, p. 403-414, 2012.
RAYNER, K. Eye movements in reading and information processing: 20 years of research. Psychological Bulletin, v. 124, n. 3, p. 372-422, 1998.
ROESSLER, E.; MITTLEMAN, G.; MOSSER, J. A.; BELLONI, E. Role of the sonic hedgehog protein in the development of the human brain and face. Pediatric Research, v. 63, n. 4, p. 445-449, 2008.
SAVAGE, J. E.; JANSEN, P. R.; STRINGER, S.; et al. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics, v. 50, p. 912-919, 2018.
TOGA, A. W.; THOMPSON, P. M. Genetics of brain structure and intelligence. Annual Review of Neuroscience, v. 28, p. 1-23, 2005.
TWIGG, S. R. F.; WILKIE, A. O. M. New insights into craniofacial malformations. Human Molecular Genetics, v. 24, R1, p. R50-R59, 2015.
ZHANG, L.; HUANG, Y.; HONG, S. et al. Pax6 Plays a Role in the Development of the Eyes and Nasal Structures. Developmental Biology, v. 333, p. 156-166, 2011.
Publicado
2024-08-01
Cómo citar
Agrela Rodrigues, F. de A., Kamimura, H.-K., Santos Nascimento, F. H. dos, Avila , E., & Oliveira Zappalá, L. (2024). Pleiotropy and Phenotypic Plasticity: Exploring the Correlation between Cognitive Traits and Craniofacial Morphology Throughout Human Development. Ciencia Latina Revista Científica Multidisciplinar, 8(4), 455-467. https://doi.org/10.37811/cl_rcm.v8i4.12285
Número
Sección
Ciencias de la Salud
Derechos de autor 2024 Fabiano de Abreu Agrela Rodrigues, Hitty-Ko Kamimura, Flávio Henrique dos Santos Nascimento, Elodia Avila , Luiza Oliveira Zappalá
Esta obra está bajo licencia internacional Creative Commons Reconocimiento 4.0.
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