Osteoporosis en el Enfermo Renal Crónico, Perspectivas de Manejo Frente a un Problema Clínico Complejo
Resumen
Los pacientes con enfermedad renal crónica (ERC) con osteoporosis coexistente se están volviendo comunes. Se sabe que muchos de los agentes terapéuticos utilizados para tratar la osteoporosis se ven afectados por la función renal. En general, se piensa que la osteoporosis en pacientes con ERC G1 a G3 se puede tratar como en pacientes sin ERC con osteoporosis. Sin embargo, en pacientes con ERC en etapa 4 o más avanzada y pacientes con ERC en diálisis con osteoporosis, los bisfosfonatos deben usarse con precaución, teniendo en cuenta el desarrollo potencial de trastornos tales como la enfermedad ósea adinámica. El uso de preparados de vitamina D en dosis bajas es relativamente seguro. En mujeres posmenopáusicas, el raloxifeno debe administrarse con precaución. Cuando se utilice denosumab, las concentraciones séricas de calcio deben controlarse cuidadosamente para prevenir el desarrollo de hipocalcemia, y deben administrarse concomitantemente preparaciones activas de vitamina D. El presente artículo proporciona una visión general del manejo de la osteoporosis en pacientes con ERC.
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Derechos de autor 2025 Angie Daniela Pedraza Jaimes , Wendy Katherine Rey Vega , Aura Michell Pacheco Quintero, José Miguel Barón Martínez , Carlos Javier Navarro Peñaranda, Luciana Sofía Uscategui Blanco , Jenner Samir Quintero Manzano , María Alejandra Velásquez Quiroga
Esta obra está bajo licencia internacional Creative Commons Reconocimiento 4.0.
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