Rabdomiolisis Como Efecto Secundario Al Manejo Con Quetiapina Y Lamotrigina, Descripción De Un Efecto Secundario Infrecuente A Raíz De Un Caso Clínico
Resumen
Objetivo: Describir un caso de rabdomiolisis asociada a uso de quetiapina y lamotrigina en adolescente tratado por trastorno afectivo bipolar. Método: Descripción del caso clínico, análisis de los factores asociados y revisión no sistemática de la literatura relevante. Resultados: Mujer joven con trastorno afectivo bipolar, tratado farmacológicamente con quetiapina y lamotrigina, que presento mialgias y artralgias con manejo instaurado por psiquiatría. La quetiapina y el ejercicio se han asociado a rabdomiolisis. No se ha encontrado el mecanismo que media tal asociación, si bien se plantea disfunción neuromuscular e incremento en la permeabilidad sarcomérica. Conclusiones: Este caso clínico permite observar la interacción compleja de los psicofármacos y la actividad física en un paciente psiquiátrico adolescente, y la aparición de una complicación médica potencialmente letal.
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Derechos de autor 2023 Luis Andrés Dulcey Sarmiento ;Juan Sebastián Theran león;Luisa Fernanda Ochoa Larrota;Carlos Julio Ramírez Zambrano;Christian Leonardo Díaz León;Edier Díaz Anaya;Claudia Lorena Trejos Marin
Esta obra está bajo licencia internacional Creative Commons Reconocimiento 4.0.
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